POGK Antibody (5Q13): sc-100648
- POGK Antibody (5Q13) is a mouse monoclonal IgG2a κ provided at 100 µg/ml
- raised against recombinant POGK of human origin
- recommended for detection of POGK of mouse, rat and human origin by WB, IP, IF and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for POGK Antibody (5Q13). This work is in progress.
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POGK Antibody (5Q13) is a mouse monoclonal IgG2a antibody that detects POGK in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). POGK, also known as BASS2 or LST003, is a 609 amino acid protein that plays a crucial role in gene expression regulation and is involved in DNA transposition, essential for genomic stability and evolution. POGK is localized in the nucleus, where POGK contains a potent N-terminal KRAB (Kruppel-associated box) domain functioning as a transcriptional repressor, influencing target gene expression. The presence of the HTH CENP-B-type DNA-binding domain allows POGK to interact with specific DNA sequences, further emphasizing POGK′s role in transcriptional regulation. Additionally, the C-terminal DDE domain, characteristic of DNA transposases and retroviral integrases, suggests POGK may be involved in integrating transposable elements into the genome, a process impacting genetic diversity and adaptability. With multifaceted functions and critical cellular localization, anti-POGK antibody (5Q13) serves as an invaluable tool for researchers studying gene regulation and transposon biology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
POGK Antibody (5Q13) | sc-100648 | 100 µg/ml | $333.00 |