PNMAL1 Antibody (D-4): sc-377122
- PNMAL1 Antibody (D-4) is a mouse monoclonal IgG1 λ PNMAL1 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 61-93 within an internal region of PNMAL1 of human origin
- PNMAL1 Antibody (D-4) is recommended for detection of PNMAL1 of human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-PNMAL1 Antibody (D-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgGλ BP-HRP (mouse IgGλ binding protein-HRP) is the preferred secondary detection reagent for PNMAL1 Antibody (D-4) for WB and IHC(P) applications. This reagent is now offered in a bundle with PNMAL1 Antibody (D-4) (see ordering information below). For additional m-IgGλ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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PNMAL1 Antibody (D-4) is a mouse monoclonal IgG1 antibody that detects PNMAL1 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). PNMAL1 (D-4) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. PNMAL1, also known as PNMA-like 1, is a 439 amino acid protein that exists in three alternatively spliced isoforms and is part of the PNMA family. PNMAL1 plays a crucial role in regulating neuronal cell death and has been implicated in various neurodegenerative diseases, making PNMAL1 an important target for research in neurobiology. PNMAL1 is encoded by a gene located on human chromosome 19q13.32, a region known for high gene density and association with several genetic disorders, including Peutz-Jeghers syndrome and spinocerebellar ataxia type 6. This chromosome region also contains key genes influencing traits such as eye and hair color, highlighting significance in both health and disease. With diverse applications and critical role in cellular processes, anti-PNMAL1 antibody (D-4) serves as an essential tool for researchers studying neuronal function and pathology.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
PNMAL1 Antibody (D-4) References:
- Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). | LaPoint, SF., et al. 2000. Adv Anat Pathol. 7: 307-21. PMID: 10976909
- Search for the second Peutz-Jeghers syndrome locus: exclusion of the STK13, PRKCG, KLK10, and PSCD2 genes on chromosome 19 and the STK11IP gene on chromosome 2. | Buchet-Poyau, K., et al. 2002. Cytogenet Genome Res. 97: 171-8. PMID: 12438709
- The DNA sequence and biology of human chromosome 19. | Grimwood, J., et al. 2004. Nature. 428: 529-35. PMID: 15057824
- Immunogenetics of killer cell immunoglobulin-like receptors. | Parham, P. 2005. Mol Immunol. 42: 459-62. PMID: 15607799
- Identification of novel oligodendroglioma-associated candidate tumor suppressor genes in 1p36 and 19q13 using microarray-based expression profiling. | Tews, B., et al. 2006. Int J Cancer. 119: 792-800. PMID: 16550607
- A novel CADASIL-causing mutation in a stroke patient. | Vikelis, M., et al. 2007. Swiss Med Wkly. 137: 323-5. PMID: 17629811
- Integrated genomic and expression profiling in mantle cell lymphoma: identification of gene-dosage regulated candidate genes. | Schraders, M., et al. 2008. Br J Haematol. 143: 210-21. PMID: 18699851
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PNMAL1 Antibody (D-4) | sc-377122 | 200 µg/ml | $316.00 | |||
PNMAL1 Antibody (D-4): m-IgGλ BP-HRP Bundle | sc-523199 | 200 µg Ab, 40 µg BP | $354.00 | |||
PNMAL1 Antibody (D-4) AC | sc-377122 AC | 500 µg/ml, 25% agarose | $416.00 | |||
PNMAL1 Antibody (D-4) HRP | sc-377122 HRP | 200 µg/ml | $316.00 | |||
PNMAL1 Antibody (D-4) FITC | sc-377122 FITC | 200 µg/ml | $330.00 | |||
PNMAL1 Antibody (D-4) PE | sc-377122 PE | 200 µg/ml | $343.00 | |||
PNMAL1 Antibody (D-4) Alexa Fluor® 488 | sc-377122 AF488 | 200 µg/ml | $357.00 | |||
PNMAL1 Antibody (D-4) Alexa Fluor® 546 | sc-377122 AF546 | 200 µg/ml | $357.00 | |||
PNMAL1 Antibody (D-4) Alexa Fluor® 594 | sc-377122 AF594 | 200 µg/ml | $357.00 | |||
PNMAL1 Antibody (D-4) Alexa Fluor® 647 | sc-377122 AF647 | 200 µg/ml | $357.00 | |||
PNMAL1 Antibody (D-4) Alexa Fluor® 680 | sc-377122 AF680 | 200 µg/ml | $357.00 | |||
PNMAL1 Antibody (D-4) Alexa Fluor® 790 | sc-377122 AF790 | 200 µg/ml | $357.00 | |||
PNMAL1 (D-4) Neutralizing Peptide | sc-377122 P | 100 µg/0.5 ml | $68.00 |