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Plk Antibody (36-298) is a mouse monoclonal IgG1 antibody that detects Plk in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Plk antibody (36-298) recognizes the polo-like kinase protein, which plays a crucial role in cell cycle regulation, particularly during mitosis. This serine/threonine kinase is essential for the proper functioning of the mitotic spindle, a structure that segregates chromosomes during cell division. Plk is predominantly located in the cytoplasm and accumulates during the S and G2 phases of the cell cycle, with levels peaking at the onset of mitosis before rapidly decreasing post-mitosis. Plk regulation is vital, as activity is closely linked to cell proliferation and the maintenance of genomic stability. Elevated expression of Plk has been observed in various tumors, suggesting potential as a biomarker for cancer progression and a target for therapeutic intervention. Plk monoclonal antibody (36-298) enables researchers to gain insights into the dynamics of cell division and implications of Plk in both normal and pathological states.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Plk Antibody (36-298) | sc-56948 | 200 µg/ml | $316.00 |