


PIS1 Antibody (D-1) is a mouse monoclonal IgG1 antibody that detects PIS1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PIS1, also known as CDIPT (CDP-diacylglycerol--inositol 3-phosphatidyltransferase) or phosphatidylinositol synthase, is a 213 amino acid multi-pass membrane protein that plays a crucial role in the biosynthesis of phosphatidylinositol (PtdIns), a vital phospholipid involved in various cellular processes, including signal transduction and membrane trafficking. PIS1 is predominantly localized to the Golgi apparatus and the cytoplasmic side of the endoplasmic reticulum, where PIS1 catalyzes the CMP-dependent exchange reaction of PtdIns, thereby maintaining cellular lipid homeostasis. PIS1 is highly conserved across species, indicating its essential function in cellular physiology, and is encoded by a gene located on human chromosome 16p11.2. With significant expression in adult liver and skeletal muscle, anti-PIS1 antibody (D-1) is an invaluable tool for researchers studying lipid metabolism and related signaling pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PIS1 Antibody (D-1) | sc-514565 | 200 µg/ml | $322.00 | |||
PIS1 Antibody (D-1): m-IgG Fc BP-HRP Bundle | sc-538663 | 200 µg Ab; 10 µg BP | $361.00 | |||
PIS1 Antibody (D-1): m-IgGκ BP-HRP Bundle | sc-536317 | 200 µg Ab; 40 µg BP | $361.00 | |||
PIS1 (D-1) Neutralizing Peptide | sc-514565 P | 100 µg/0.5 ml | $69.00 |