Pin1 Antibody (F-7): sc-271441
- Pin1 Antibody (F-7) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 116-146 near the C-terminus of Pin1 of human origin
- recommended for detection of Pin1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- See Pin1 (G-8): sc-46660 for Pin1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Pin1 Antibody (F-7). This work is in progress.
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Pin1 Antibody (F-7) is a mouse monoclonal IgG1 kappa light chain antibody designed to recognize Pin1, also known as peptidylprolyl cis/trans isomerase NIMA-interacting 1. Anti-Pin1 antibody (F-7) targets an epitope mapping between amino acids 116-146 near the C-terminus of human Pin1, ensuring precise and reliable detection. Pin1 is a crucial enzyme characterized by its unique structure, which includes a WW domain responsible for binding phosphorylated serine/threonine-proline motifs and a peptidylprolyl isomerase (PPIase) domain that catalyzes the cis/trans isomerization of proline residues. This structural configuration enables Pin1 to regulate the conformation and function of its substrates, playing a vital role in controlling cell cycle progression, signal transduction, and protein stability. Proper functioning of Pin1 is essential for maintaining cellular homeostasis, and dysregulation has been implicated in various diseases, including cancer and neurodegenerative disorders. Pin1 monoclonal antibody (F-7) exhibits broad species reactivity, effectively detecting Pin1 from mouse, rat, human, as well as additional species such as equine, canine, bovine, and porcine origins, and is validated for use in western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA) applications. Anti-Pin1 antibody (F-7) high specificity and versatility make it an indispensable tool for researchers investigating the structural and functional dynamics of Pin1 in diverse biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Pin1 Antibody (F-7) | sc-271441 | 200 µg/ml | $316.00 | |||
Pin1 (F-7) Neutralizing Peptide | sc-271441 P | 100 µg/0.5 ml | $68.00 |