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Pin1 Antibody (8C10) is a mouse monoclonal IgG1 antibody engineered to recognize Pin1, also known as peptidylprolyl cis/trans isomerase, NIMA-interacting 1. Anti-Pin1 antibody (8C10) is raised against recombinant human Pin1 and targets a unique epitope, ensuring accurate and reliable detection. Pin1 is a pivotal peptidyl-prolyl isomerase located in both the nucleus and cytoplasm of cells, where Pin1 regulates the conformation and function of phosphorylated serine/threonine-proline motifs in various substrates. This regulation is essential for controlling critical cellular processes such as cell cycle progression, signal transduction, and protein stability, highlighting Pin1′s importance in maintaining cellular homeostasis and involvement in diseases like cancer and neurodegenerative disorders. Pin1 monoclonal antibody (8C10) demonstrates broad species reactivity, effectively detecting Pin1 from mouse, rat, human, and canine origins, and is validated for use in western blotting (WB) and immunoprecipitation (IP) applications. Anti-Pin1 antibody (8C10) serves as a valuable tool for researchers studying the mechanistic roles of Pin1 in cellular functions and disease mechanisms. Available in a non-conjugated form, Pin1 (8C10) antibody supports diverse experimental workflows, facilitating advanced investigations into the localization, expression, and interaction dynamics of Pin1 within different cellular contexts.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Pin1 Antibody (8C10) | sc-81533 | 50 µg/0.5 ml | $316.00 |