Date published: 2025-12-7

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pICln Antibody (C-5): sc-393525

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Datasheets
  • pICln Antibody (C-5) is a mouse monoclonal IgG2a κ, cited in 4 publications, provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 159-186 within an internal region of pICln of human origin
  • recommended for detection of pICln of mouse, rat, human and origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
  • m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for pICln Antibody (C-5) for WB and IHC(P) applications. These reagents are now offered in bundles with pICln Antibody (C-5) (see ordering information below).

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pICln Antibody (C-5) is a mouse monoclonal IgG2a antibody that detects pICln in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). pICln, a highly conserved and ubiquitously expressed protein, primarily localizes to the cytoplasm and plays a crucial role in the assembly of the spliceosome by interacting with Sm proteins. Anti-pICln antibody (C-5) recognizes a protein essential for the proper formation of small nuclear ribonucleoproteins (snRNPs), which are vital for pre-mRNA splicing. Additionally, pICln has been implicated in the regulation of swelling-activated anion channels, highlighting its multifaceted role in cellular processes. The gene encoding human pICln is located on chromosome 11q14.1, and its function in both the methylosome complex and as a potential channel regulator underscores its importance in maintaining cellular homeostasis and facilitating efficient gene expression. pICln monoclonal antibody (C-5) serves as an invaluable tool for researchers studying RNA processing and related cellular mechanisms.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

pICln Antibody (C-5)

sc-393525
200 µg/ml
$316.00

pICln Antibody (C-5): m-IgG Fc BP-HRP Bundle

sc-538237
200 µg Ab; 10 µg BP
$354.00

pICln Antibody (C-5): m-IgGκ BP-HRP Bundle

sc-535811
200 µg Ab; 40 µg BP
$354.00

pICln Antibody (C-5): m-IgG2a BP-HRP Bundle

sc-548243
200 µg Ab; 10 µg BP
$354.00

pICln (C-5) Neutralizing Peptide

sc-393525 P
100 µg/0.5 ml
$68.00

What application is the blocking peptide sc-393525 P appropriate for?

Asked by: Germaine
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Produced excellent immunofluorescence nuclearProduced excellent immunofluorescence nuclear and cytoplasmic staining in methanol-fixed HeLa cells. -SCBT QC
Date published: 2015-04-13
Rated 5 out of 5 by from Satisfactory Western Blot data of pICln expressionSatisfactory Western Blot data of pICln expression in Hep G2, ECV304, HL-60 and HeLa whole cell lysates. -SCBT QC
Date published: 2014-07-01
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pICln Antibody (C-5) is rated 5.0 out of 5 by 2.
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