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pICln Antibody (C-5) is a mouse monoclonal IgG2a antibody that detects pICln in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). pICln, a highly conserved and ubiquitously expressed protein, primarily localizes to the cytoplasm and plays a crucial role in the assembly of the spliceosome by interacting with Sm proteins. Anti-pICln antibody (C-5) recognizes a protein essential for the proper formation of small nuclear ribonucleoproteins (snRNPs), which are vital for pre-mRNA splicing. Additionally, pICln has been implicated in the regulation of swelling-activated anion channels, highlighting its multifaceted role in cellular processes. The gene encoding human pICln is located on chromosome 11q14.1, and its function in both the methylosome complex and as a potential channel regulator underscores its importance in maintaining cellular homeostasis and facilitating efficient gene expression. pICln monoclonal antibody (C-5) serves as an invaluable tool for researchers studying RNA processing and related cellular mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
pICln Antibody (C-5) | sc-393525 | 200 µg/ml | $316.00 | |||
pICln Antibody (C-5): m-IgG Fc BP-HRP Bundle | sc-538237 | 200 µg Ab; 10 µg BP | $354.00 | |||
pICln Antibody (C-5): m-IgGκ BP-HRP Bundle | sc-535811 | 200 µg Ab; 40 µg BP | $354.00 | |||
pICln Antibody (C-5): m-IgG2a BP-HRP Bundle | sc-548243 | 200 µg Ab; 10 µg BP | $354.00 | |||
pICln (C-5) Neutralizing Peptide | sc-393525 P | 100 µg/0.5 ml | $68.00 |