PGRP-Iβ Antibody (6D652): sc-71884
- PGRP-Iβ Antibody (6D652) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against amino acids 95-110 of PGRP-Iβ of human origin
- recommended for detection of PGRP-Iβ of mouse, rat, human and porcine origin by WB
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for PGRP-Iβ Antibody (6D652). This work is in progress.
PGRP-Iβ Antibody (6D652) is a mouse monoclonal IgG1 antibody that detects PGRP-Iβ in mouse, rat, human, and porcine samples through western blotting (WB). PGRP-Iβ is a crucial member of the peptidoglycan recognition protein family, which plays a significant role in the immune response by recognizing peptidoglycan, a vital component of bacterial cell walls. PGRP-Iβ is primarily expressed in the esophagus, with lesser expression in the tonsils and thymus, highlighting its importance in mucosal immunity. PGRP-Iβ functions as a pattern recognition receptor, binding to peptidoglycan and Gram-positive bacteria, thereby facilitating the activation of antimicrobial pathways. Notably, PGRP-Iβ is a transmembrane protein consisting of 373 amino acids and features at least three highly conserved C-terminal PGRP domains, which are essential for its interaction with bacterial components. The structural integrity of these domains is critical for PGRP-Iβ′s ability to initiate immune responses, making PGRP-Iβ a key player in the host defense against bacterial infections. Anti-PGRP-Iβ antibody (6D652) is an invaluable tool for researchers studying the mechanisms of innate immunity and the role of peptidoglycan recognition in various species.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PGRP-Iβ Antibody (6D652) | sc-71884 | 100 µg/ml | $322.00 |