PGM 3 Antibody (E-6): sc-390280
- PGM 3 Antibody (E-6) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against amino acids 243-542 mapping at the C-terminus of PGM 3 of human origin
- recommended for detection of PGM 3 of human origin by WB, IP, IF and ELISA
- m-IgG2a BP-HRP is the preferred secondary detection reagent for PGM 3 Antibody (E-6) for WB applications. This reagent is now offered in a bundle with PGM 3 Antibody (E-6) (see ordering information below).
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PGM 3 Antibody (E-6) is a mouse monoclonal IgG2a antibody that detects phosphoglucomutase 3 (PGM 3) in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PGM 3 plays a crucial role in carbohydrate metabolism, specifically in the interconversion of glucose-1-phosphate and glucose-6-phosphate, which is vital for both glycogenolysis and glycogenesis. This enzymatic activity is essential for maintaining glucose homeostasis and energy production in cells, particularly in tissues with high metabolic demands such as the heart, liver, and pancreas. PGM 3 is a 542 amino acid protein expressed ubiquitously, with notable exceptions in lung tissue, and functions as a monomer that binds one magnesium ion per subunit, which is critical for enzymatic activity. The presence of multiple isozymes, including PGM 1, PGM 2, PGM 4, and Aciculin, highlights the evolutionary adaptation of this enzyme family to fulfill similar metabolic roles across different tissues. Anti-PGM 3 antibody (E-6) is an invaluable tool for researchers studying metabolic pathways and disorders related to glycogen metabolism, providing insights into the physiological and pathological roles of this important enzyme.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PGM 3 Antibody (E-6) | sc-390280 | 200 µg/ml | $322.00 | |||
PGM 3 Antibody (E-6): m-IgG2a BP-HRP Bundle | sc-546070 | 200 µg Ab; 10 µg BP | $361.00 |