pescadillo Antibody (G-11): sc-515273

pescadillo Antibody (G-11) is a mouse monoclonal IgG2a antibody that detects pescadillo in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Pescadillo, also known as PES1, is a crucial protein involved in cell cycle regulation and ribosome biogenesis, playing a significant role in cellular proliferation and growth. Anti-pescadillo antibody (G-11) has been shown to detect increased levels in various cancers, including human breast carcinoma and glioblastoma, indicating pescadillo′s potential as a biomarker for tumor progression. Pescadillo is predominantly expressed in the liver, kidney, and testis, with minimal expression in skeletal muscle, highlighting specific roles in these tissues. Notably, pescadillo contains a BRCT (breast cancer C-terminal) domain, which is essential for protein-protein interactions and is implicated in DNA damage response pathways. The presence of this domain suggests that pescadillo may interact with other critical proteins involved in cell cycle control and tumor suppression, further underscoring pescadillo′s importance in maintaining cellular homeostasis and potential as a therapeutic target in cancer treatment. Anti-pescadillo antibody (G-11) serves as an invaluable tool for researchers studying the mechanisms of cell proliferation and pescadillo′s role in various diseases.

The preferred pescadillo antibody is pescadillo Antibody (H-10): sc-166300.