Peroxin 5 Antibody (50): sc-136030

Peroxin 5 Antibody (50) is a mouse monoclonal IgG1 antibody that detects Peroxin 5 in mouse samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Peroxin 5, also known as the peroxisome targeting signal 1 (PTS1) receptor, plays a crucial role in the import of proteins into peroxisomes, which are essential organelles involved in various metabolic processes, including the breakdown of very long-chain fatty acids and the detoxification of hydrogen peroxide. Peroxin 5 is primarily located in the cytosol, where anti-Peroxin 5 antibody (50) can detect interactions with proteins containing the PTS1 signal, facilitating their transport to peroxisomes. This localization is vital because Peroxin 5 ensures that enzymes and other proteins necessary for peroxisomal function are correctly delivered, thereby maintaining cellular homeostasis and preventing metabolic disorders. Mutations in the Pex5 gene can lead to severe peroxisome biogenesis disorders, such as Zellweger syndrome, underscoring the importance of Peroxin 5 in cellular health. Peroxin 5 monoclonal antibody (50) is an invaluable tool for researchers studying peroxisome function and related pathologies, providing insights into the mechanisms of protein import and the consequences of its dysregulation.

The preferred Peroxin 5 antibody is Peroxin 5 Antibody (B-3): sc-137103.