Anti-Pericentrin 1 Antibody (D-4) is a mouse monoclonal IgG1 κ Pericentrin 1 antibody, cited in 3 publications, provided at 200 µg/ml
raised against amino acids 1-300 mapping at the N-terminus of Pericentrin 1 of human origin
Anti-Pericentrin 1 Antibody (D-4) is recommended for detection of Pericentrin 1 of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-Pericentrin 1 Antibody (D-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Pericentrin 1 (D-4): sc-376111.
At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Pericentrin 1 Antibody (D-4). This work is in progress.
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Pericentrin 1 Antibody (D-4) is a high quality monoclonal Pericentrin 1 antibody (also designated Pericentrin 1 antibody) suitable for the detection of the Pericentrin 1 protein of mouse, rat and human origin. Pericentrin 1 Antibody (D-4) is available as both the non-conjugated anti-Pericentrin 1 antibody form, as well as multiple conjugated forms of anti-Pericentrin 1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Pericentrin 1 (Nuclear pore complex protein Nup85) is a 656 amino acid member of the nucleoporin Nup85 family. Pericentrin 1 is an essential component of the nuclear pore complex (NPC) and is likely required for NPC assembly and maintenance. Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through NPCs embedded in the nuclear envelope. The Pericentrin 1 containing NPC subcomplex, Nup107-160, works to organize RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex is likely required for spindle assembly during mitosis and for membrane clustering of CCL2-activated CCR2. Pericentrin 1 also acts as a regulator of microtubule nucleation by associating with gamma-tubulin and anchors the PKA holoenzyme at the association site. The gene encoding human pericentrin 1 is found at chromosome 17q25.2.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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