CD31/PECAM-1 Antibody (10G9): sc-13537
- CD31/PECAM-1 Antibody (10G9) is a mouse monoclonal IgG1 κ, cited in 31 publications, provided at 200 µg/ml
- raised against full length PECAM-1 of human origin
- CD31/PECAM-1 Antibody (10G9) is recommended for detection of PECAM-1 of human origin by IF, IHC(P), FCM and ELISA
- Anti-CD31/PECAM-1 Antibody (10G9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CD31/PECAM-1 Antibody (10G9). This work is in progress.
QUICK LINKS
PECAM-1 Antibody (10G9) is a mouse monoclonal IgG1 kappa light chain antibody that detects human PECAM-1 by immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Anti-PECAM-1 antibody (10G9) is available in non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. PECAM-1, also known as CD31, is a crucial glycoprotein expressed on monocytes, neutrophils, platelets, and a subset of T cells, playing a vital role in mediating cell-cell adhesion and signaling during inflammatory responses and angiogenesis. PECAM-1 is predominantly located at intercellular junctions of endothelial cells, where PECAM-1 facilitates leukocyte migration across vascular endothelium, a process essential for immune surveillance and tissue repair. Understanding PECAM-1 localization and function is important, as PECAM-1 dysregulation can contribute to various pathological conditions, including chronic inflammation and tumor metastasis. PECAM-1 interaction with other adhesion molecules, such as integrins, further underscores PECAM-1′s significance in maintaining vascular integrity and regulating immune responses.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD31/PECAM-1 Antibody (10G9) | sc-13537 | 200 µg/ml | $316.00 | |||
CD31/PECAM-1 Antibody (10G9) AC | sc-13537 AC | 500 µg/ml, 25% agarose | $416.00 | |||
CD31/PECAM-1 Antibody (10G9) HRP | sc-13537 HRP | 200 µg/ml | $316.00 | |||
CD31/PECAM-1 Antibody (10G9) FITC | sc-13537 FITC | 200 µg/ml | $330.00 | |||
CD31/PECAM-1 Antibody (10G9) PE | sc-13537 PE | 200 µg/ml | $343.00 | |||
CD31/PECAM-1 Antibody (10G9) Alexa Fluor® 488 | sc-13537 AF488 | 200 µg/ml | $357.00 | |||
CD31/PECAM-1 Antibody (10G9) Alexa Fluor® 546 | sc-13537 AF546 | 200 µg/ml | $357.00 | |||
CD31/PECAM-1 Antibody (10G9) Alexa Fluor® 594 | sc-13537 AF594 | 200 µg/ml | $357.00 | |||
CD31/PECAM-1 Antibody (10G9) Alexa Fluor® 647 | sc-13537 AF647 | 200 µg/ml | $357.00 | |||
CD31/PECAM-1 Antibody (10G9) Alexa Fluor® 680 | sc-13537 AF680 | 200 µg/ml | $357.00 | |||
CD31/PECAM-1 Antibody (10G9) Alexa Fluor® 790 | sc-13537 AF790 | 200 µg/ml | $357.00 |