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PDCL3 Antibody (J-16) is a mouse monoclonal IgG1 antibody that detects PDCL3 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). PDCL3, also known as phosducin-like 3, VIAF1, VIAF, PHLP3, or HTPHLP, is a crucial protein that plays a significant role in the chaperone-assisted folding of other proteins, particularly β Tubulin and Actin, which are essential for proper cell cycle progression. By localizing to the cytoplasm, PDCL3 interacts with the cytosolic chaperonin complex (CCT) and modulates CCT′s ATPase activity, thereby influencing the folding process of substrates. This regulation is vital because misfolded proteins can lead to cellular dysfunction and contribute to various diseases. PDCL3′s ability to repress CCT′s ATPase activity highlights PDCL3′s importance in maintaining cellular homeostasis and ensuring that proteins are correctly folded and functional. Anti-PDCL3 antibody (J-16) serves as an invaluable tool for researchers studying protein folding and related cellular processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PDCL3 Antibody (J-16) | sc-100806 | 50 µg/0.5 ml | $339.00 |