PDCD1LG2/PD-L2 Antibody (XX19): sc-80285
- PDCD1LG2/PD-L2 Antibody (XX19) is a mouse monoclonal IgG2b, cited in 2 publications, provided at 100 µg/ml
- raised against the extracellular domain of PD-L2 of human origin
- recommended for detection of PD-L2 of human origin by WB, IF and IHC(P)
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for PDCD1LG2/PD-L2 Antibody (XX19). This work is in progress.
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SEE ALSO...
Pdcd-1L2 Antibody (XX19) is a mouse monoclonal IgG2b light chain antibody that detects Pdcd-1L2 in human samples through applications such as western blotting (WB), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). Pdcd-1L2, also known as programmed cell death ligand-2, is a 73 amino acid type I transmembrane protein that plays a crucial role in the immune response by interacting with the PD-1 receptor on T cells, thereby modulating their activity. This interaction helps maintain immune tolerance and prevent excessive immune responses that could lead to autoimmune diseases. Pdcd-1L2 features a signal sequence, immunoglobulin V-like and C-like domains, a transmembrane region, and a cytoplasmic tail, which are essential for function and localization within the cell membrane. The gene encoding Pdcd-1L2 is located on human chromosome 9p24.2, and expression on various immune and non-immune cells suggests a critical checkpoint role in regulating T cell activation and survival. Anti-Pdcd-1L2 antibody (XX19) enables researchers to gain insights into immune regulation mechanisms and potential therapeutic targets for enhancing anti-tumor immunity or treating autoimmune disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PDCD1LG2/PD-L2 Antibody (XX19) | sc-80285 | 100 µg/ml | $322.00 |