Pax-7 Antibody (6290C1a): sc-130019
- Pax-7 Antibody (6290C1a) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against a recombinant protein corresponding to an internal region of Pax-7 of human origin
- recommended for detection of Pax-7 of human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Pax-7 Antibody (6290C1a). This work is in progress.
Pax-7 Antibody (6290C1a) is a mouse monoclonal IgG1 antibody raised against a recombinant protein corresponding to an internal region of human Pax-7. Pax-7, also known as Paired box protein Pax-7 or HUP1, is a nuclear transcription factor that plays a crucial role in embryonic development and muscle cell differentiation. Structurally, Pax-7 contains a paired box domain and a homeodomain, both of which are DNA-binding motifs essential for regulating gene expression. This structural configuration allows Pax-7 to bind specific DNA sequences, influencing the development of skeletal muscle and the maintenance of satellite cells in adult muscle tissue. The importance of Pax-7′s structure lies in its ability to control gene networks involved in muscle regeneration and repair. Aberrations in the PAX7 gene, such as chromosomal translocations, have been associated with rhabdomyosarcoma 2 (RMS2), also known as alveolar rhabdomyosarcoma, highlighting its significance in cancer biology. Anti-Pax-7 antibody (6290C1a) shows reactivity with human Pax-7 in applications like western blotting (WB) and immunoprecipitation (IP), making Pax-7 (6290C1a) antibody a valuable tool for researchers studying muscle development, stem cell biology, and the molecular mechanisms underlying certain muscular diseases and cancers.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Pax-7 Antibody (6290C1a) | sc-130019 | 100 µg/ml | $333.00 |