Parvovirus Antibody (CPV1-2A1): sc-57961

Parvovirus Antibody (CPV1-2A1) is a mouse monoclonal IgG2a antibody that detects Parvovirus in Parvovirus species by immunofluorescence (IF) and immunohistochemistry with paraffin-embedded sections (IHCP). Anti-Parvovirus antibody (CPV1-2A1) is available as a non-conjugated format, specifically targeting the canine parvovirus (CPV) and feline panleucopenia virus (FPV). Parvovirus is a genus within the Parvoviridae family, characterized by a linear, non-segmented single-stranded DNA genome, measuring around 5 kilobases in length. The viral capsid is composed of three proteins—VP1, VP2, and VP3—that assemble into a robust icosahedral structure. This configuration provides resistance to environmental factors such as pH and solvents and withstands temperatures up to 50°C, ensuring viral stability and infectivity. Hairpin structures formed by approximately 115 nucleotide sequences at both the 5′ and 3′ ends of the genome play a significant role in viral replication and packaging processes. Parvoviruses infect a wide range of mammalian species, with Parvovirus B19 being associated with erythema infectiosum, a mild but contagious illness that primarily affects erythroid cells. This poses particular concern for pregnant women, as transmission to the fetus can lead to potential complications. Anti-Parvovirus antibody (CPV1-2A1) accurately detects viral proteins for research and diagnostic applications, contributing to understanding parvoviral infections and their implications in both veterinary and human medicine.

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Parvovirus Antibody (CPV1-2A1) References:

1. Parvovirus replication.  |  Berns, KI. 1990. Microbiol Rev. 54: 316-29. PMID: 2215424
2. Clinical manifestations of human parvovirus B19 in adults.  |  Woolf, AD., et al. 1989. Arch Intern Med. 149: 1153-6. PMID: 2541666
3. Human parvovirus arthropathy.  |  White, DG., et al. 1985. Lancet. 1: 419-21. PMID: 2857804
4. Human parvovirus-associated arthritis: a clinical and laboratory description.  |  Reid, DM., et al. 1985. Lancet. 1: 422-5. PMID: 2857805
5. Human parvovirus infection in pregnancy and hydrops fetalis.  |  Anand, A., et al. 1987. N Engl J Med. 316: 183-6. PMID: 3025725
6. Characterization of capsid and noncapsid proteins of B19 parvovirus propagated in human erythroid bone marrow cell cultures.  |  Ozawa, K. and Young, N. 1987. J Virol. 61: 2627-30. PMID: 3599184
7. Parvovirus infections and hypoplastic crisis in sickle-cell anaemia.  |  Pattison, JR., et al. 1981. Lancet. 1: 664-5. PMID: 6110886
8. Human parvovirus, the cause of erythema infectiosum (fifth disease)?  |  Anderson, MJ., et al. 1983. Lancet. 1: 1378. PMID: 6134148
9. The incidence of human parvovirus B19 infection during pregnancy and its impact on perinatal outcome.  |  Gratacós, E., et al. 1995. J Infect Dis. 171: 1360-3. PMID: 7751717
10. Chronic parvovirus B19 infection and systemic necrotising vasculitis: opportunistic infection or aetiological agent?  |  Finkel, TH., et al. 1994. Lancet. 343: 1255-8. PMID: 7910276

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Parvovirus Antibody (CPV1-2A1) has 3 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Parvovirus Antibody (CPV1-2A1) Specifications

Alternate Product Name: Parvovirus

Product Clone Name: CPV1-2A1

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a

Amino Acids:

Epitope Target: Parvovirus

Epitope Species:

Product Reactivity/Detection: canine parvovirus (CPV) and feline panleucopenia virus (FPV)

Species Reactivity/Detection: Parvovirus

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: IF, IHC(P)

Vialing Information: Each vial contains 100 µg IgG_2a in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 3 citations in various scientific publications

Available Conjugates/Forms for Parvovirus Antibody (CPV1-2A1): N/A