PARP-10 Antibody (6D643): sc-71851
- PARP-10 Antibody (6D643) is a rat monoclonal rat IgG1, cited in 1 publications, provided at 200 µg/ml
- raised against PARP-10 of human origin
- recommended for detection of PARP-10 of mouse, rat and human origin by WB, IP and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for PARP-10 Antibody (6D643). This work is in progress.
PARP-10 Antibody (6D643) is a rat monoclonal IgG1 antibody raised against human PARP-10 and is reactive with mouse, rat, and human samples, making anti-PARP-10 antibody (6D643) suitable for applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). PARP-10 is a member of the poly(ADP-ribose) polymerase family, a group of enzymes that play important roles in cellular processes like DNA repair and chromatin remodeling. PARP-10 is primarily associated with regulating cell proliferation and survival. PARP-10 enzyme localizes to both the nuclear and cytoplasmic compartments, where PARP-10 exerts function by inhibiting the oncogenic activities of proteins such as c-Myc and E1A. By adding ADP-ribose units to target proteins, PARP-10 modifies their function, suppressing the uncontrolled cell growth that is characteristic of cancerous transformation. PARP-10′s role in controlling cell proliferation is vital, as PARP-10 helps maintain proper cellular growth and division, preventing oncogenic transformation. Studying PARP-10 through tools like PARP-10 (6D643) antibody is crucial for understanding PARP-10′s contribution to tumor suppression and the broader regulation of cell cycle dynamics.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PARP-10 Antibody (6D643) | sc-71851 | 200 µg/ml | $316.00 |