PAR4 Antibody (4H12E9): sc-130079
- PAR4 Antibody (4H12E9) is a mouse monoclonal IgG1 provided at 200 µg/ml
- raised against a recombinant protein corresponding to amino acids 1-330 of PAR4 of human origin
- recommended for detection of PAR4 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- See PAR4 (A-10): sc-1666 for PAR4 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for PAR4 Antibody (4H12E9). This work is in progress.
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SEE ALSO...
PAR4 Antibody (4H12E9) is a mouse monoclonal IgG1 antibody that detects PAR4 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). PAR4, or prostate apoptosis response 4, plays a crucial role in the regulation of apoptosis, particularly in cells undergoing programmed cell death. Anti-PAR4 antibody (4H12E9) specifically recognizes PAR4 in cells entering apoptosis and is not induced by growth factor stimulation, oxidative stress, necrosis, or growth arrest, highlighting its unique function in maintaining cellular homeostasis. The PAR4 gene encodes a protein that features a putative nuclear localization signal and a carboxy-terminal leucine zipper, which are important for its function in the nucleus and may facilitate interactions with other nuclear proteins involved in apoptotic signaling pathways. Understanding the role of PAR4 in apoptosis is vital, as dysregulation of this process can lead to various diseases, including cancer. PAR4 (4H12E9) monoclonal antibody serves as an invaluable tool for researchers studying apoptosis and its implications in cancer biology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PAR4 Antibody (4H12E9) | sc-130079 | 200 µg/ml | $316.00 |