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PAPSS 2 Antibody (SQ-19) is a mouse monoclonal IgG1 antibody that detects PAPSS 2 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). PAPSS 2, a crucial enzyme in the sulfate activation pathway, plays a significant role in sulfate assimilation, which is vital for numerous biological processes, including the synthesis of sulfated biomolecules such as glycosaminoglycans and proteoglycans. These biomolecules are essential for maintaining the structural integrity of tissues and facilitating cell signaling. PAPSS 2′s bifunctional nature, exhibiting both adenosine 5′-phosphosulfate kinase and ATP sulfurylase activities, underscores PAPSS 2′s importance in regulating sulfate levels within cells. Notably, defects in the PAPSS 2 gene can lead to the Pakistani type of spondyloepimetaphyseal dysplasia, a condition characterized by skeletal abnormalities, highlighting the critical role of PAPSS 2 in normal skeletal development. With proven effectiveness in studying sulfate metabolism and related disorders, anti-PAPSS 2 antibody (SQ-19) serves as an invaluable tool for researchers investigating these pathways and their implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PAPSS 2 Antibody (SQ-19) | sc-100801 | 100 µg/ml | $339.00 |