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Pan-Cytokeratin Antibody (HEP 111) is a mouse monoclonal IgG1 antibody that detects pan-Cytokeratin in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Anti-pan-Cytokeratin antibody (HEP 111) targets a diverse group of intermediate filament proteins that are crucial for maintaining the structural integrity of epithelial cells. These proteins are essential for cellular differentiation and tissue specialization while serving as important biomarkers for various malignancies. For instance, the expression of specific cytokeratins can indicate the type of epithelial tissue involved in a tumor, with cytokeratins 10 and 13 being highly expressed in certain squamous cell carcinomas, while cytokeratin 18 is prevalent in many adenocarcinomas and basal cell carcinomas. Understanding the expression patterns of these cytokeratins is vital for accurate tumor characterization and can significantly influence treatment decisions, making pan-Cytokeratin (HEP 111) monoclonal antibody an invaluable tool in both research and clinical diagnostics.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
pan-Cytokeratin Antibody (HEP 111) | sc-53401 | 200 µg/ml | $316.00 |