Date published: 2025-9-20

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pan-Cytokeratin Antibody (80): sc-58825

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Datasheets
  • pan-Cytokeratin Antibody (80) is a mouse monoclonal IgG1, cited in 4 publications, provided at 100 µg/ml
  • recommended for detection of most keratins of mouse, rat and human origin by WB, IP, IF and IHC(P); non cross-reactive with neurofilament, Vimentin, GFAP or Desmin
  • See pan-Cytokeratin (C11): sc-8018 for pan-Cytokeratin antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for pan-Cytokeratin Antibody (80). This work is in progress.

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Pan-Cytokeratin Antibody (80) is a mouse monoclonal IgG1 antibody that detects pan-Cytokeratin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). Anti-pan-Cytokeratin antibody (80) targets a diverse group of intermediate filament proteins that are crucial for maintaining the structural integrity of epithelial cells. These proteins are expressed in pairs within both keratinized and non-keratinized epithelial tissues, playing a vital role in cellular differentiation and tissue specialization. The presence of specific cytokeratins can serve as important biomarkers for various types of tumors; for instance, cytokeratins 10 and 13 are often found in elevated levels in certain squamous cell carcinomas, while cytokeratin 18 is predominantly expressed in adenocarcinomas and basal cell carcinomas. Understanding the expression patterns of these cytokeratins is essential for the accurate characterization of malignant tumors, making pan-Cytokeratin (80) monoclonal antibody an invaluable tool in cancer research and diagnostics.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

pan-Cytokeratin Antibody (80)

sc-58825
100 µg/ml
$316.00

Can sc-58825: pan-Cytokeratin (80) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: Cweed
Thank you for your question. Yes, sc-58825: pan-Cytokeratin (80) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-03-24
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Rated 3 out of 5 by from Postive WB data in HeLaPostive WB data in HeLa, A-431 and Hep G2 whole cell lysates. -SCBT QC
Date published: 2015-01-12
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pan-Cytokeratin Antibody (80) is rated 3.0 out of 5 by 1.
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