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Pan-Cytokeratin Antibody (80) is a mouse monoclonal IgG1 antibody that detects pan-Cytokeratin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). Anti-pan-Cytokeratin antibody (80) targets a diverse group of intermediate filament proteins that are crucial for maintaining the structural integrity of epithelial cells. These proteins are expressed in pairs within both keratinized and non-keratinized epithelial tissues, playing a vital role in cellular differentiation and tissue specialization. The presence of specific cytokeratins can serve as important biomarkers for various types of tumors; for instance, cytokeratins 10 and 13 are often found in elevated levels in certain squamous cell carcinomas, while cytokeratin 18 is predominantly expressed in adenocarcinomas and basal cell carcinomas. Understanding the expression patterns of these cytokeratins is essential for the accurate characterization of malignant tumors, making pan-Cytokeratin (80) monoclonal antibody an invaluable tool in cancer research and diagnostics.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
pan-Cytokeratin Antibody (80) | sc-58825 | 100 µg/ml | $316.00 |