pan-Cytokeratin Antibody (80): sc-58825
- pan-Cytokeratin Antibody (80) is a mouse monoclonal IgG1, cited in 4 publications, provided at 100 µg/ml
- recommended for detection of most keratins of mouse, rat and human origin by WB, IP, IF and IHC(P); non cross-reactive with neurofilament, Vimentin, GFAP or Desmin
- See pan-Cytokeratin (C11): sc-8018 for pan-Cytokeratin antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for pan-Cytokeratin Antibody (80). This work is in progress.
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Pan-Cytokeratin Antibody (80) is a mouse monoclonal IgG1 antibody that detects pan-Cytokeratin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). Anti-pan-Cytokeratin antibody (80) targets a diverse group of intermediate filament proteins that are crucial for maintaining the structural integrity of epithelial cells. These proteins are expressed in pairs within both keratinized and non-keratinized epithelial tissues, playing a vital role in cellular differentiation and tissue specialization. The presence of specific cytokeratins can serve as important biomarkers for various types of tumors; for instance, cytokeratins 10 and 13 are often found in elevated levels in certain squamous cell carcinomas, while cytokeratin 18 is predominantly expressed in adenocarcinomas and basal cell carcinomas. Understanding the expression patterns of these cytokeratins is essential for the accurate characterization of malignant tumors, making pan-Cytokeratin (80) monoclonal antibody an invaluable tool in cancer research and diagnostics.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
pan-Cytokeratin Antibody (80) References:
- Central granular cell odontogenic tumor: the first reported case in Oriental people and literature review. | Chiang, CT., et al. 2014. J Formos Med Assoc. 113: 321-5. PMID: 24428977
- Bone marrow-derived cells contribute to regeneration of injured prostate epithelium and stroma. | Nakata, W., et al. 2015. Prostate. 75: 806-14. PMID: 25663042
- Simultaneous Detection of Disseminated and Circulating Tumor Cells in Primary Breast Cancer Patients. | Hartkopf, AD., et al. 2016. Cancer Res Treat. 48: 115-24. PMID: 25687853
- A comparative study of the effects of 4-META/MMA-TBB resin and cyanoacrylate on wound healing of skin defects. | Kidokoro, R., et al. 2016. J Biomed Mater Res B Appl Biomater. 104: 197-203. PMID: 25715705
- A Biphasic Pleural Tumor with Features of an Epithelioid and Small Cell Mesothelioma: Morphologic and Molecular Findings. | Hackman, S., et al. 2016. Case Rep Pathol. 2016: 1532424. PMID: 27403364
- Ex vivo culture of oral keratinocytes using direct explant cell culture technique. | Shwetha, HR., et al. 2019. J Oral Maxillofac Pathol. 23: 243-247. PMID: 31516231
- Assessment of individual tumor buds using keratin immunohistochemistry: moderate interobserver agreement suggests a role for machine learning. | Bokhorst, JM., et al. 2020. Mod Pathol. 33: 825-833. PMID: 31844269
- Central Odontogenic Fibroma with the Presence of Large Fibroblasts of Varying Morphology. | Costa, V., et al. 2021. Head Neck Pathol. 15: 663-667. PMID: 32865727
- Co-expression of CD34 and h-caldesmon in a benign meningioma-like dermal neoplasm, a case report. | Kussaibi, H. 2020. Dermatol Reports. 12: 8994. PMID: 33408843
- A rare presentation of primary cardiac diffuse large B‑cell lymphoma: A case report. | Jiang, H., et al. 2024. Oncol Lett. 27: 40. PMID: 38108070
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
pan-Cytokeratin Antibody (80) | sc-58825 | 100 µg/ml | $322.00 |