pan 14-3-3 Antibody (B-11): sc-133232
- pan 14-3-3 Antibody (B-11) is a mouse monoclonal IgG1 κ, cited in 11 publications, provided at 200 µg/ml
- raised against amino acids 1-246 representing full length 14-3-3 β of human origin
- Anti-pan 14-3-3 Antibody (B-11) is recommended for detection of pan 14-3-3 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-pan 14-3-3 Antibody (B-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for pan 14-3-3 Antibody (B-11). This work is in progress.
pan 14-3-3 Antibody (B-11) is a mouse monoclonal IgG1 kappa light chain antibody that detects pan 14-3-3 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). pan 14-3-3 (B-11) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. 14-3-3 proteins play a crucial role in regulating numerous cellular processes, particularly those associated with cancer biology, such as apoptosis, mitogenic signaling, and cell-cycle checkpoints. 14-3-3 proteins are located primarily in the cytoplasm and nucleus, where 14-3-3 proteins interact with a wide range of target proteins, influencing their activity and stability. 14-3-3 proteins′ ability to sequester ligands in the cytoplasm is particularly important, as this sequestration prevents ligand degradation and modulates interactions with other cellular components. Such dynamic regulation is essential for maintaining cellular homeostasis and ensuring proper cellular responses to various stimuli. Loss of 14-3-3 expression can lead to dysregulation of these processes, contributing to the development of various diseases, including cancer.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
pan 14-3-3 Antibody (B-11) | sc-133232 | 200 µg/ml | $322.00 | |||
pan 14-3-3 Antibody (B-11) AC | sc-133232 AC | 500 µg/ml, 25% agarose | $424.00 | |||
pan 14-3-3 Antibody (B-11) HRP | sc-133232 HRP | 200 µg/ml | $322.00 | |||
pan 14-3-3 Antibody (B-11) FITC | sc-133232 FITC | 200 µg/ml | $336.00 | |||
pan 14-3-3 Antibody (B-11) PE | sc-133232 PE | 200 µg/ml | $349.00 | |||
pan 14-3-3 Antibody (B-11) Alexa Fluor® 488 | sc-133232 AF488 | 200 µg/ml | $364.00 | |||
pan 14-3-3 Antibody (B-11) Alexa Fluor® 546 | sc-133232 AF546 | 200 µg/ml | $364.00 | |||
pan 14-3-3 Antibody (B-11) Alexa Fluor® 594 | sc-133232 AF594 | 200 µg/ml | $364.00 | |||
pan 14-3-3 Antibody (B-11) Alexa Fluor® 647 | sc-133232 AF647 | 200 µg/ml | $364.00 | |||
pan 14-3-3 Antibody (B-11) Alexa Fluor® 680 | sc-133232 AF680 | 200 µg/ml | $364.00 | |||
pan 14-3-3 Antibody (B-11) Alexa Fluor® 790 | sc-133232 AF790 | 200 µg/ml | $364.00 |