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PAFAH1B3 Antibody (37-K) is a mouse monoclonal IgG1 antibody that detects PAFAH1B3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PAFAH1B3, also known as the 29kDa subunit of the platelet-activating factor acetylhydrolase complex, plays a crucial role in the hydrolysis of pro-inflammatory phospholipids, thereby modulating inflammatory responses and maintaining cellular homeostasis. PAFAH1B3 is primarily located in the cytoplasm and is essential for brain development and function, as PAFAH1B3 is part of the heterotrimeric PAFAH1B complex, which includes the regulatory subunit LIS1 and the catalytic subunits PAFAH1B2 and PAFAH1B3. The interaction between PAFAH1B3 and PAFAH1B2 is vital for the stability and catalytic activity of the enzyme, as these subunits form heterodimers with high affinity. The proper functioning of PAFAH1B3 is important not only for neurodevelopment but also for the regulation of various signaling pathways, making PAFAH1B3 a significant target for research in neurobiology and inflammation. anti-PAFAH1B3 antibody (37-K) is an invaluable tool for researchers studying the intricate roles of PAFAH1B3 in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PAFAH1B3 Antibody (37-K) | sc-81950 | 100 µg/ml | $339.00 |