PA Antibody (BAP0103) is a mouse monoclonal IgG2b antibody that detects protective antigen (PA) of Bacillus anthracis by enzyme-linked immunosorbent assay (ELISA). PA (BAP0103) antibody plays a crucial role in understanding the pathogenic mechanisms of anthrax, as PA is essential for the delivery of lethal factor (LF) and edema factor (EF) into host cells, facilitating their toxic effects. PA serves as the binding component that allows LF and EF to enter target cells, where they can disrupt cellular processes and lead to severe disease outcomes. This interaction is vital for the bacterium′s virulence, making PA a key target for therapeutic interventions and vaccine development. PA is the primary component of anthrax vaccines, as PA elicits a robust immune response that confers protective immunity against the disease. The ability to produce recombinant PA in large quantities is critical for vaccine formulation, underscoring PA′s importance in both research and clinical applications. Using PA (BAP0103) antibody in your experiments enables effective study of anthrax pathogenesis dynamics and contributes to developing effective countermeasures against this serious infectious disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PA Antibody (BAP0103) | sc-52125 | 100 µg/ml | $322.00 |