Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Bacillus anthracis, a Gram-positive bacterium, is capsulogenic and toxinogenic and is the causative agent of anthrax. Bacillus anthracis secretes two toxins, which are composed of three proteins: the protective antigen (PA), the lethal factor (LF) and the edema factor (EF). PA and LF comprise a lethal toxin, which provokes a subite death in animals, whereas the edema toxin, comprised of PA and EF, induces edema. The edema and the lethal factors are internalized into the target cells via the protective antigen. PA is the target-cell binding protein and is common to the two effector molecules, LF and EF, which exert their toxic effects once they are translocated to the cytosol by PA. PA is the major component of vaccines against anthrax since it confers protective immunity. The large-scale production of recombinant protein-based anthrax vaccines requires overexpression of the PA protein. LF plays an important role in the pathogenesis of anthrax. In addition, EF and LF exert adenylate cyclase and metalloprotease activity, respectively.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn