p38 alpha MAPK14 Antibody (G-7): sc-166357

p38 alpha MAPK14 Antibody (G-7) is a mouse monoclonal IgG1 kappa light chain antibody designed to target p38 alpha MAPK14, also known as p38α, CSBP, MXI2, or MAP kinase 14, across multiple species including mouse, rat, human, bovine, porcine, and avian. p38 alpha MAPK14 (G-7) antibody specifically recognizes an epitope located between amino acids 329-360 at the C-terminus of mouse p38 alpha MAPK14, making it suitable for applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). p38 alpha MAPK14 is a pivotal member of the mitogen-activated protein kinase (MAPK) family, characterized by its single protein kinase domain which is crucial for phosphorylating target proteins. Structurally, p38 alpha MAPK14 relies on magnesium as a cofactor to facilitate ATP-dependent phosphorylation, a process essential for activating the kinase through the addition of phosphate groups to threonine and tyrosine residues. These post-translational modifications are vital for p38 alpha MAPK14′s involvement in key cellular processes such as signal transduction, cytokine production, cell proliferation, differentiation, and apoptosis. The precise structural configuration of p38 alpha MAPK14 allows participation in various signaling pathways, thereby influencing numerous biological functions and responses to stress stimuli. anti-p38 alpha MAPK14 antibody (G-7) enables researchers to accurately study the structural and functional dynamics of this kinase, enhancing the understanding of its role in health and disease. Available in both non-conjugated and various conjugated forms, including horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® variants, p38 alpha MAPK14 (G-7) antibody offers versatility for diverse experimental needs.

The preferred p38 alpha/beta MAPK antibody is p38 alpha/beta MAPK Antibody (A-12): sc-7972.