CDKN2A/p16 Antibody (JC8): sc-56330
- CDKN2A/p16 Antibody (JC8) is a mouse monoclonal IgG2a, cited in 299 publications, provided at 200 µg/ml
- raised against full length recombinant p16 INK4A of human origin
- CDKN2A/p16 Antibody (JC8) is recommended for detection of p16 INK4A of human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-CDKN2A/p16 Antibody (JC8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of CDKN2A/p16 (JC8): sc-56330.
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for CDKN2A/p16 Antibody (JC8) for WB and IHC(P) applications. These reagents are now offered in bundles with CDKN2A/p16 Antibody (JC8) (see ordering information below).
p16 INK4A Antibody (JC8) is a mouse monoclonal IgG2a antibody that detects p16 INK4A of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). p16 INK4A (JC8) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. p16 INK4A functions as a tumor suppressor by inhibiting cyclin-dependent kinase 4 (Cdk4), thereby preventing retinoblastoma protein (Rb) phosphorylation and blocking cell cycle progression from G1 phase to S phase. This regulatory function maintains proper cell cycle control and prevents uncontrolled cell proliferation, a hallmark of cancer. p16 INK4A gene alterations, including homozygous deletions and point mutations, are frequently found in various human tumors, highlighting its significance in tumorigenesis. Using anti-p16 INK4A antibody (JC8) enables researchers to investigate cell cycle regulation mechanisms and p16 INK4A dysregulation in cancer biology.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CDKN2A/p16 Antibody (JC8) | sc-56330 | 200 µg/ml | $316.00 | |||
CDKN2A/p16INK4a Antibody (JC8): m-IgG Fc BP-HRP Bundle | sc-525655 | 200 µg Ab; 10 µg BP | $354.00 | |||
CDKN2A/p16INK4a Antibody (JC8): m-IgG2a BP-HRP Bundle | sc-546354 | 200 µg Ab; 10 µg BP | $354.00 | |||
CDKN2A/p16INK4a Antibody (JC8) AC | sc-56330 AC | 500 µg/ml, 25% agarose | $416.00 | |||
CDKN2A/p16INK4a Antibody (JC8) HRP | sc-56330 HRP | 200 µg/ml | $316.00 | |||
CDKN2A/p16INK4a Antibody (JC8) FITC | sc-56330 FITC | 200 µg/ml | $330.00 | |||
CDKN2A/p16INK4a Antibody (JC8) PE | sc-56330 PE | 200 µg/ml | $343.00 | |||
CDKN2A/p16INK4a Antibody (JC8) Alexa Fluor® 488 | sc-56330 AF488 | 200 µg/ml | $357.00 | |||
CDKN2A/p16INK4a Antibody (JC8) Alexa Fluor® 546 | sc-56330 AF546 | 200 µg/ml | $357.00 | |||
CDKN2A/p16INK4a Antibody (JC8) Alexa Fluor® 594 | sc-56330 AF594 | 200 µg/ml | $357.00 | |||
CDKN2A/p16INK4a Antibody (JC8) Alexa Fluor® 647 | sc-56330 AF647 | 200 µg/ml | $357.00 | |||
CDKN2A/p16INK4a Antibody (JC8) Alexa Fluor® 680 | sc-56330 AF680 | 200 µg/ml | $357.00 | |||
CDKN2A/p16INK4a Antibody (JC8) Alexa Fluor® 790 | sc-56330 AF790 | 200 µg/ml | $357.00 |