p14ARF Antibody (14P02): sc-73434
- p14ARF Antibody (14P02) is a mouse monoclonal IgG1 κ, cited in 4 publications, provided at 200 µg/ml
- raised against the N-terminus of p14 ARF of human origin
- recommended for detection of p14 ARF of human origin by WB, IP, IF and IHC(P)
- See p14ARF (ARF 4C6/4): sc-53392 for p14ARF antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for p14ARF Antibody (14P02). This work is in progress.
p14 ARF Antibody (14P02) is a mouse monoclonal IgG1 antibody that detects p14 ARF in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. p14 ARF plays a crucial role in regulating the cell cycle by acting as a tumor suppressor, particularly through interaction with MDM2 protein. p14 ARF (14P02) antibody recognizes a protein that stabilizes p53 by inhibiting MDM2, which is responsible for targeting p53 for degradation. By preventing p53 degradation, p14 ARF facilitates the activation of p53-dependent pathways that lead to cell cycle arrest and apoptosis in response to cellular stress or DNA damage. p14 ARF′s ability to modulate MDM2 and p21 levels further underscores p14 ARF′s importance in maintaining genomic integrity and preventing tumorigenesis. anti-p14 ARF antibody (14P02) serves as an essential tool for researchers studying cell cycle regulation mechanisms and p14 ARF′s implications in cancer biology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p14ARF Antibody (14P02) | sc-73434 | 200 µg/ml | $316.00 |