p-Stat6 Antibody (16E12): sc-81525
- p-Stat6 Antibody (16E12) is a mouse monoclonal IgG1, cited in 1 publications, provided at 50 µg/0.5 ml
- raised against a synthetic phosphopeptide corresponding to the region surrounding phosphorylated Tyr 641 of Stat6 of human origin
- recommended for detection of Tyr 641 phosphorylated Stat6 of human origin by WB, IP and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for p-Stat6 Antibody (16E12). This work is in progress.
p-Stat6 Antibody (16E12) is a mouse monoclonal IgG1 antibody that detects p-Stat6 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). p-Stat6 plays a crucial role in the signaling pathways activated by interleukin-4 (IL-4) and other cytokines, where p-Stat6 is phosphorylated on specific tyrosine and serine residues, leading to dimerization and subsequent translocation to the nucleus. Once in the nucleus, p-Stat6 binds to specific response elements in the promoters of target genes, thereby functioning as a sequence-specific transcription factor that regulates gene expression critical for immune responses and cell differentiation. The ability of p-Stat6 to mediate IL-4 signaling is essential for the full activation of immune cells, influencing processes such as T cell differentiation and the production of immunoglobulins. Anti-p-Stat6 antibody (16E12) enables researchers to effectively study the dynamics of IL-4 signaling and its implications in various biological contexts, including allergic responses and immune regulation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p-Stat6 Antibody (16E12) | sc-81525 | 50 µg/0.5 ml | $322.00 |