p-PDGF Receptor beta/PDGFRB Antibody (H-3): sc-365465

p-PDGFR-β Antibody (H-3) is a mouse monoclonal IgG3 antibody that detects platelet-derived growth factor receptor beta (PDGFR-β) in mouse, rat, and human samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-PDGFR-β antibody (H-3) specifically recognizes the phosphorylated form of PDGFR-β, which plays a crucial role in cellular signaling pathways that regulate cell growth, survival, and migration. PDGFR-β is primarily located on the cell surface, where PDGFR-β interacts with PDGF isoforms to initiate a cascade of intracellular signaling events. PDGFR-β is essential for various physiological processes, including embryonic development, wound healing, and tissue repair. Importantly, activation of PDGFR-β through ligand binding leads to autophosphorylation at specific tyrosine residues, which is vital for recruiting downstream signaling molecules such as phosphatidylinositol-3 kinase. Proper functioning of PDGFR-β is critical, as dysregulation of PDGFR-β signaling can contribute to pathological conditions, including cancer and fibrotic diseases. Using PDGFR-β monoclonal antibody (H-3), researchers can gain valuable insights into PDGFR-β′s role in various biological contexts and disease states.

The preferred PDGF Receptor beta/PDGFRB antibody is PDGF Receptor beta/PDGFRB Antibody (D-6): sc-374573.