p-MYPT1 Antibody (A-6): sc-377542
- p-MYPT1 Antibody (A-6) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- Anti-p-MYPT1 Antibody (A-6) is recommended for detection of Ser 903 phosphorylated MYPT1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine
- Anti-p-MYPT1 Antibody (A-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for p-MYPT1 Antibody (A-6) for WB applications. This reagent is now offered in a bundle with p-MYPT1 Antibody (A-6) (see ordering information below).
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p-MYPT1 Antibody (A-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects Ser 903 phosphorylated MYPT1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). p-MYPT1 (A-6) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Myosin phosphatase target subunit 1 (MYPT1), also known as the myosin-binding subunit of myosin phosphatase, plays a crucial role in regulating the interaction between actin and myosin, which is essential for muscle contraction and cellular motility. The phosphorylation of MYPT1 at specific sites, such as Ser 903, is vital for modulating activity and, consequently, the phosphorylation state of myosin light chains. This regulation is particularly important in smooth muscle cells, where MYPT1′s activity influences calcium sensitivity and contraction dynamics. MYPT1 is localized on stress fibers and is strategically positioned near the cell membrane and at cell-cell junctions, allowing effective regulation of myosin phosphatase activity in response to various signaling pathways. The intricate balance of MYPT1 phosphorylation and dephosphorylation is essential for maintaining proper muscle function and cellular responses to stimuli, making anti-MYPT1 antibody (A-6) a valuable tool for researchers studying these critical processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p-MYPT1 Antibody (A-6) | sc-377542 | 200 µg/ml | $322.00 | |||
p-MYPT1 Antibody (A-6): m-IgG Fc BP-HRP Bundle | sc-526112 | 200 µg Ab; 10 µg BP | $361.00 | |||
p-MYPT1 Antibody (A-6) AC | sc-377542 AC | 500 µg/ml, 25% agarose | $424.00 | |||
p-MYPT1 Antibody (A-6) HRP | sc-377542 HRP | 200 µg/ml | $322.00 | |||
p-MYPT1 Antibody (A-6) FITC | sc-377542 FITC | 200 µg/ml | $336.00 | |||
p-MYPT1 Antibody (A-6) PE | sc-377542 PE | 200 µg/ml | $349.00 | |||
p-MYPT1 Antibody (A-6) Alexa Fluor® 488 | sc-377542 AF488 | 200 µg/ml | $364.00 | |||
p-MYPT1 Antibody (A-6) Alexa Fluor® 546 | sc-377542 AF546 | 200 µg/ml | $364.00 | |||
p-MYPT1 Antibody (A-6) Alexa Fluor® 594 | sc-377542 AF594 | 200 µg/ml | $364.00 | |||
p-MYPT1 Antibody (A-6) Alexa Fluor® 647 | sc-377542 AF647 | 200 µg/ml | $364.00 | |||
p-MYPT1 Antibody (A-6) Alexa Fluor® 680 | sc-377542 AF680 | 200 µg/ml | $364.00 | |||
p-MYPT1 Antibody (A-6) Alexa Fluor® 790 | sc-377542 AF790 | 200 µg/ml | $364.00 | |||
p-MYPT1 (A-6) Neutralizing Peptide | sc-377542 P | 100 µg/0.5 ml | $69.00 |