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P-cadherin Antibody (12H6) is a mouse monoclonal IgG1 antibody that detects P-cadherin in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). P-cadherin, a member of the cadherin family, plays a crucial role in cell adhesion and is essential for maintaining tissue integrity and architecture. P-cadherin is primarily located at the cell membrane, where P-cadherin forms adherens junctions that facilitate strong intercellular connections. Proper localization of P-cadherin is vital for cellular signaling and communication, influencing processes such as tissue morphogenesis and repair. Additionally, P-cadherin′s interaction with cytoplasmic proteins, including β-catenin, is significant for regulating adhesive properties and signaling pathways, which can impact cellular behavior in both normal and pathological states. Anti-P-cadherin antibody (12H6) is an invaluable tool for researchers studying the dynamics of cell adhesion and the implications of cadherin function in various diseases, including cancer, where altered expression of P-cadherin can contribute to tumor progression and metastasis.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
P-cadherin Antibody (12H6) | sc-53981 | 200 µg/ml | $316.00 | |||
P-cadherin Antibody (12H6): m-IgGκ BP-HRP Bundle | sc-534209 | 200 µg Ab; 40 µg BP | $354.00 | |||
P-cadherin Antibody (12H6): m-IgG1 BP-HRP Bundle | sc-538862 | 200 µg Ab; 20 µg BP | $354.00 |