Date published: 2025-10-15

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P-cadherin Antibody (12H6): sc-53981

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Datasheets
  • P-cadherin Antibody (12H6) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
  • raised against P-cadherin fusion protein of human origin
  • recommended for detection of P-cadherin of human origin by WB, IP and IF
  • See P-cadherin (A-10): sc-74545 for P-cadherin antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for P-cadherin Antibody (12H6) for WB applications. These reagents are now offered in bundles with P-cadherin Antibody (12H6) (see ordering information below).

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    P-cadherin Antibody (12H6) is a mouse monoclonal IgG1 antibody that detects P-cadherin in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). P-cadherin, a member of the cadherin family, plays a crucial role in cell adhesion and is essential for maintaining tissue integrity and architecture. P-cadherin is primarily located at the cell membrane, where P-cadherin forms adherens junctions that facilitate strong intercellular connections. Proper localization of P-cadherin is vital for cellular signaling and communication, influencing processes such as tissue morphogenesis and repair. Additionally, P-cadherin′s interaction with cytoplasmic proteins, including β-catenin, is significant for regulating adhesive properties and signaling pathways, which can impact cellular behavior in both normal and pathological states. Anti-P-cadherin antibody (12H6) is an invaluable tool for researchers studying the dynamics of cell adhesion and the implications of cadherin function in various diseases, including cancer, where altered expression of P-cadherin can contribute to tumor progression and metastasis.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    P-cadherin Antibody (12H6)

    sc-53981
    200 µg/ml
    $316.00

    P-cadherin Antibody (12H6): m-IgGκ BP-HRP Bundle

    sc-534209
    200 µg Ab; 40 µg BP
    $354.00

    P-cadherin Antibody (12H6): m-IgG1 BP-HRP Bundle

    sc-538862
    200 µg Ab; 20 µg BP
    $354.00

    How much sample do you recommend loading on the gel for Western blot detection using P-cadherin (12H6): sc-53981?

    Asked by: DefinitelyNotMatt
    We recommend loading 40–60 µg whole cell lysate, 10–20 µg nuclear extract, 5-10 µg transfected lysate, or 10–20 ng purified protein per lane. A link to our complete Western blotting protocol is provided here for your reference: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
    Answered by: Technical Support
    Date published: 2017-03-01
    • y_2025, m_10, d_14, h_6CST
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    Rated 3 out of 5 by from Used transfected lysate that produced a coupleUsed transfected lysate that produced a couple of strong bands at expected mw -SCBT QC
    Date published: 2015-04-02
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    P-cadherin Antibody (12H6) is rated 3.0 out of 5 by 1.
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