p-c-Jun Antibody (C-J 4C4/1): sc-53182
- p-c-Jun Antibody (C-J 4C4/1) is a mouse monoclonal IgG1 κ, cited in 12 publications, provided at 200 µg/ml
- raised against p-c-Jun phosphorylated at Thr 91 and Thr 93
- Anti-p-c-Jun Antibody (C-J 4C4/1) is recommended for detection of Thr 91 and Thr 93 phosphrylated c-Jun of mouse, rat and human origin by WB, IP and IHC(P)
- Anti-p-c-Jun Antibody (C-J 4C4/1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for p-c-Jun Antibody (C-J 4C4/1) for WB and IHC(P) applications. This reagent is now offered in a bundle with p-c-Jun Antibody (C-J 4C4/1) (see ordering information below).
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p-c-Jun Antibody (C-J 4C4/1) is a mouse monoclonal IgG1 kappa light chain antibody that detects phosphorylated c-Jun, specifically at Thr 91 and Thr 93, in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunohistochemistry. anti-p-c-Jun antibody (C-J 4C4/1) is available in non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for different experimental needs. c-Jun plays a crucial role in cellular processes as a key component of the transcription factor AP-1, which regulates gene expression in response to growth factors and stress signals. This regulation is vital for cell proliferation, differentiation, and apoptosis, making c-Jun significant in oncogenic pathways. Phosphorylation of c-Jun enhances transcriptional activity, allowing heterodimer formation with Fos proteins, which bind to the TPA-response element with high affinity, influencing gene expression in tumor promotion and progression. Understanding c-Jun dynamics and interactions with other proteins, such as Ha-Ras which augments activity, is critical for elucidating molecular mechanisms in cancer development and progression.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p-c-Jun Antibody (C-J 4C4/1) | sc-53182 | 200 µg/ml | $322.00 | |||
p-c-Jun Antibody (C-J 4C4/1): m-IgG Fc BP-HRP Bundle | sc-525581 | 200 µg Ab; 10 µg BP | $361.00 | |||
p-c-Jun Antibody (C-J 4C4/1) AC | sc-53182 AC | 500 µg/ml, 25% agarose | $424.00 | |||
p-c-Jun Antibody (C-J 4C4/1) HRP | sc-53182 HRP | 200 µg/ml | $322.00 | |||
p-c-Jun Antibody (C-J 4C4/1) FITC | sc-53182 FITC | 200 µg/ml | $336.00 | |||
p-c-Jun Antibody (C-J 4C4/1) PE | sc-53182 PE | 200 µg/ml | $349.00 | |||
p-c-Jun Antibody (C-J 4C4/1) Alexa Fluor® 488 | sc-53182 AF488 | 200 µg/ml | $364.00 | |||
p-c-Jun Antibody (C-J 4C4/1) Alexa Fluor® 546 | sc-53182 AF546 | 200 µg/ml | $364.00 | |||
p-c-Jun Antibody (C-J 4C4/1) Alexa Fluor® 594 | sc-53182 AF594 | 200 µg/ml | $364.00 | |||
p-c-Jun Antibody (C-J 4C4/1) Alexa Fluor® 647 | sc-53182 AF647 | 200 µg/ml | $364.00 | |||
p-c-Jun Antibody (C-J 4C4/1) Alexa Fluor® 680 | sc-53182 AF680 | 200 µg/ml | $364.00 | |||
p-c-Jun Antibody (C-J 4C4/1) Alexa Fluor® 790 | sc-53182 AF790 | 200 µg/ml | $364.00 |