Date published: 2026-4-29

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p-beta-catenin Antibody (24E1): sc-57534

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Datasheets
  • p-beta-catenin Antibody (24E1) is a mouse monoclonal IgG1, cited in 10 publications, provided at 50 µg/0.5 ml
  • raised against a synthetic phosphopeptide of β-catenin of human origin
  • recommended for detection of Tyr 86 phosphorylated β-catenin of mouse, rat and human origin by WB and IP
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for p-beta-catenin Antibody (24E1). This work is in progress.
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p-β-catenin Antibody (24E1) is a mouse monoclonal IgG1 antibody that detects β-catenin in mouse, rat, and human samples through applications such as western blotting (WB) and immunoprecipitation (IP). Anti-β-catenin antibody (24E1) specifically recognizes the phosphorylated form of β-catenin, a crucial protein involved in cell adhesion and signaling pathways. β-catenin monoclonal antibody (24E1) targets proteins primarily located in the cytoplasm and nucleus, where β-catenin plays a pivotal role in the Wnt signaling pathway, essential for cellular processes including cell proliferation, differentiation, and migration. β-catenin′s accumulation in the nucleus can lead to target gene activation promoting cell growth and survival, potentially contributing to oncogenesis when dysregulated. β-catenin′s interaction with other proteins, such as tumor suppressor APC, is critical for maintaining cellular homeostasis; any disruption can lead to aberrant signaling and tumor development. Anti-β-catenin antibody (24E1) serves as an invaluable tool for researchers studying cell signaling mechanisms and β-catenin′s implications in cancer biology.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

p-beta-catenin Antibody (24E1)

sc-57534
50 µg/0.5 ml
$322.00

I am using p-β-catenin (24E1): sc-57534 antibody for immunoprecipitation, how much antibody should I use?

Asked by: Trav11
Thank you for your question. We recommend using 1–10 µl (i.e., 0.2–2 µg) of antibody with 1 ml of cell lysate. However, optimal antibody concentration should be determined by titration. Please find our full immunoprecipitation protocol here: https://www.scbt.com/scbt/resources/protocols/immunoprecipitation-western-blots
Answered by: Technical Support
Date published: 2017-03-24
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Rated 4 out of 5 by from Clean single band for WB in nonClean single band for WB in non-stimulated (A), and pervanadate stimulated (B) SW480 whole cell lysates. -SCBT QC
Date published: 2013-06-26
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p-beta-catenin Antibody (24E1) is rated 4.0 out of 5 by 1.
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