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p-β-catenin Antibody (24E1) is a mouse monoclonal IgG1 antibody that detects β-catenin in mouse, rat, and human samples through applications such as western blotting (WB) and immunoprecipitation (IP). Anti-β-catenin antibody (24E1) specifically recognizes the phosphorylated form of β-catenin, a crucial protein involved in cell adhesion and signaling pathways. β-catenin monoclonal antibody (24E1) targets proteins primarily located in the cytoplasm and nucleus, where β-catenin plays a pivotal role in the Wnt signaling pathway, essential for cellular processes including cell proliferation, differentiation, and migration. β-catenin′s accumulation in the nucleus can lead to target gene activation promoting cell growth and survival, potentially contributing to oncogenesis when dysregulated. β-catenin′s interaction with other proteins, such as tumor suppressor APC, is critical for maintaining cellular homeostasis; any disruption can lead to aberrant signaling and tumor development. Anti-β-catenin antibody (24E1) serves as an invaluable tool for researchers studying cell signaling mechanisms and β-catenin′s implications in cancer biology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p-beta-catenin Antibody (24E1) | sc-57534 | 50 µg/0.5 ml | $322.00 |