Ovol2 Antibody (E-9): sc-515001
- Ovol2 Antibody (E-9) is a mouse monoclonal IgG2b κ Ovol2 antibody, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 222-237 within an internal region of Ovol2 of human origin
- Ovol2 Antibody (E-9) is recommended for detection of Ovol2 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-Ovol2 Antibody (E-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for ChIP application (sc-515001 X, 200 µg/0.1 ml)
- m-IgGκ BP-HRP is the preferred secondary detection reagent for Ovol2 Antibody (E-9) for WB applications. This reagent is now offered in a bundle with Ovol2 Antibody (E-9) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
QUICK LINKS
Ovol2 Antibody (E-9) is a mouse monoclonal IgG2b kappa light chain antibody that detects Ovol2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-Ovol2 antibody (E-9) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Ovol2, a member of the Ovo family of zinc-finger transcription factors, plays a crucial role in regulating gene expression during development, particularly in neural and vascular processes. Ovol2 maintains the balance between cell proliferation and differentiation, which is vital for proper embryonic development. Ovol2 interacts with other transcription factors and signaling pathways, including Wnt and TGF-β/BMP, to modulate the expression of genes involved in these processes. Understanding Ovol2 function is important, as dysregulation can lead to developmental disorders and contribute to various diseases. Ovol2 (E-9) antibody effectively detects this protein across multiple species, making Ovol2 (E-9) monoclonal antibody a valuable tool for researchers studying developmental biology and related fields.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ovol2 Antibody (E-9) References:
- Ovol2, a mammalian homolog of Drosophila ovo: gene structure, chromosomal mapping, and aberrant expression in blind-sterile mice. | Li, B., et al. 2002. Genomics. 80: 319-25. PMID: 12213202
- Ovol1 regulates meiotic pachytene progression during spermatogenesis by repressing Id2 expression. | Li, B., et al. 2005. Development. 132: 1463-73. PMID: 15716349
- The mouse Ovol2 gene is required for cranial neural tube development. | Mackay, DR., et al. 2006. Dev Biol. 291: 38-52. PMID: 16423343
- Ovol1 regulates the growth arrest of embryonic epidermal progenitor cells and represses c-myc transcription. | Nair, M., et al. 2006. J Cell Biol. 173: 253-64. PMID: 16636146
- Strain-dependent perinatal lethality of Ovol1-deficient mice and identification of Ovol2 as a downstream target of Ovol1 in skin epidermis. | Teng, A., et al. 2007. Biochim Biophys Acta. 1772: 89-95. PMID: 17049212
- Ovol1 represses its own transcription by competing with transcription activator c-Myb and by recruiting histone deacetylase activity. | Nair, M., et al. 2007. Nucleic Acids Res. 35: 1687-97. PMID: 17311813
- Ovol2/Movo, a homologue of Drosophila ovo, is required for angiogenesis, heart formation and placental development in mice. | Unezaki, S., et al. 2007. Genes Cells. 12: 773-85. PMID: 17573777
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ovol2 Antibody (E-9) | sc-515001 | 200 µg/ml | $322.00 | |||
Ovol2 Antibody (E-9): m-IgGκ BP-HRP Bundle | sc-524896 | 200 µg Ab, 40 µg BP | $361.00 | |||
Ovol2 Antibody (E-9) X | sc-515001 X | 200 µg/0.1 ml | $322.00 | |||
Ovol2 Antibody (E-9) AC | sc-515001 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Ovol2 Antibody (E-9) HRP | sc-515001 HRP | 200 µg/ml | $322.00 | |||
Ovol2 Antibody (E-9) FITC | sc-515001 FITC | 200 µg/ml | $336.00 | |||
Ovol2 Antibody (E-9) PE | sc-515001 PE | 200 µg/ml | $349.00 | |||
Ovol2 Antibody (E-9) Alexa Fluor® 488 | sc-515001 AF488 | 200 µg/ml | $364.00 | |||
Ovol2 Antibody (E-9) Alexa Fluor® 546 | sc-515001 AF546 | 200 µg/ml | $364.00 | |||
Ovol2 Antibody (E-9) Alexa Fluor® 594 | sc-515001 AF594 | 200 µg/ml | $364.00 | |||
Ovol2 Antibody (E-9) Alexa Fluor® 647 | sc-515001 AF647 | 200 µg/ml | $364.00 | |||
Ovol2 Antibody (E-9) Alexa Fluor® 680 | sc-515001 AF680 | 200 µg/ml | $364.00 | |||
Ovol2 Antibody (E-9) Alexa Fluor® 790 | sc-515001 AF790 | 200 µg/ml | $364.00 | |||
Ovol2 (E-9) Neutralizing Peptide | sc-515001 P | 100 µg/0.5 ml | $69.00 |