OR5T1 Antibody (G-2): sc-398550

OR5T1 Antibody (G-2) is a mouse monoclonal IgM antibody that detects OR5T1 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-OR5T1 antibody (G-2) is available as a non-conjugated isotype antibody. OR5T1, also known as olfactory receptor 5T1 or OR11-179, is a 326 amino acid multi-pass membrane protein that plays a crucial role in the olfactory system by interacting with odorant molecules to initiate neuronal responses, ultimately leading to the perception of smell. OR5T1 is part of the G-protein coupled receptor 1 family and shares a seven transmembrane domain structure with many neurotransmitter and hormone receptors, highlighting its importance in sensory signal transduction. The gene encoding OR5T1 is located on human chromosome 11q12.1, which houses over 1,400 genes and comprises nearly 4% of the human genome. Defects in genes mapping to this chromosome are associated with various syndromes, including Jervell and Lange-Nielsen syndrome and Jacobsen syndrome, underscoring the significance of olfactory receptors in human health. The OR5T1 gene is part of the largest gene family in the genome, emphasizing the complexity and diversity of olfactory signaling pathways.

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OR5T1 Antibody (G-2) References:

1. Hereditary angioedema. Long-term follow-up of 88 patients. Experience of the Argentine Allergy and Immunology Institute.  |  Fabiani, JE., et al. 2000. Allergol Immunopathol (Madr). 28: 267-71. PMID: 11270087
2. Smith-Lemli-Opitz syndrome and the DHCR7 gene.  |  Jira, PE., et al. 2003. Ann Hum Genet. 67: 269-80. PMID: 12914579
3. The human olfactory receptor gene family.  |  Malnic, B., et al. 2004. Proc Natl Acad Sci U S A. 101: 2584-9. PMID: 14983052
4. The pathogenesis and treatment of acid sphingomyelinase-deficient Niemann-Pick disease.  |  Schuchman, EH. 2007. J Inherit Metab Dis. 30: 654-63. PMID: 17632693
5. Jervell and Lange-Nielsen syndrome in Norwegian children: aspects around cochlear implantation, hearing, and balance.  |  Siem, G., et al. 2008. Ear Hear. 29: 261-9. PMID: 18595190
6. Chromosomal microarray mapping suggests a role for BSX and Neurogranin in neurocognitive and behavioral defects in the 11q terminal deletion disorder (Jacobsen syndrome).  |  Coldren, CD., et al. 2009. Neurogenetics. 10: 89-95. PMID: 18855024
7. An intronic mutation leading to incomplete skipping of exon-2 in KCNQ1 rescues hearing in Jervell and Lange-Nielsen syndrome.  |  Bhuiyan, ZA., et al. 2008. Prog Biophys Mol Biol. 98: 319-27. PMID: 19027783

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-OR5T1 Antibody (G-2) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-OR5T1 Antibody (G-2) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

OR5T1 Antibody (G-2) Specifications

Alternate Product Name: OR5T1

Product Clone Name: G-2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 1-17

Epitope Target: OR5T1

Epitope Species: human

Product Reactivity/Detection: OR5T1

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for OR5T1 Antibody (G-2): P: Blocking Peptide