OR56B1 Antibody (E-9): sc-515497

OR56B1 Antibody (E-9) is a mouse monoclonal IgM antibody that detects OR56B1 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-OR56B1 antibody (E-9) is available as the non-conjugated form. OR56B1 , also known as olfactory receptor 56B1 or OR11-65, is a 324 amino acid multi-pass membrane protein that plays a crucial role in the olfactory system by interacting with odorant molecules in the nasal epithelium. This interaction initiates a neuronal response that leads to the perception of smell, making olfactory receptors essential for sensory processing. OR56B1 belongs to the G-protein coupled receptor 1 family and shares a seven transmembrane domain structure with many neurotransmitter and hormone receptors, highlighting its importance in signal transduction. The gene encoding OR56B1 is located on human chromosome 11p15.4, which houses over 1,400 genes and comprises nearly 4% of the human genome. Defects in genes mapping to this chromosome have been associated with various syndromes, including Jervell and Lange-Nielsen syndrome and Jacobsen syndrome, underscoring the significance of olfactory receptors in both health and disease.

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OR56B1 Antibody (E-9) References:

1. Hereditary angioedema. Long-term follow-up of 88 patients. Experience of the Argentine Allergy and Immunology Institute.  |  Fabiani, JE., et al. 2000. Allergol Immunopathol (Madr). 28: 267-71. PMID: 11270087
2. Smith-Lemli-Opitz syndrome and the DHCR7 gene.  |  Jira, PE., et al. 2003. Ann Hum Genet. 67: 269-80. PMID: 12914579
3. The human olfactory receptor gene family.  |  Malnic, B., et al. 2004. Proc Natl Acad Sci U S A. 101: 2584-9. PMID: 14983052
4. The pathogenesis and treatment of acid sphingomyelinase-deficient Niemann-Pick disease.  |  Schuchman, EH. 2007. J Inherit Metab Dis. 30: 654-63. PMID: 17632693
5. Jervell and Lange-Nielsen syndrome in Norwegian children: aspects around cochlear implantation, hearing, and balance.  |  Siem, G., et al. 2008. Ear Hear. 29: 261-9. PMID: 18595190
6. Chromosomal microarray mapping suggests a role for BSX and Neurogranin in neurocognitive and behavioral defects in the 11q terminal deletion disorder (Jacobsen syndrome).  |  Coldren, CD., et al. 2009. Neurogenetics. 10: 89-95. PMID: 18855024
7. An intronic mutation leading to incomplete skipping of exon-2 in KCNQ1 rescues hearing in Jervell and Lange-Nielsen syndrome.  |  Bhuiyan, ZA., et al. 2008. Prog Biophys Mol Biol. 98: 319-27. PMID: 19027783

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-OR56B1 Antibody (E-9) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-OR56B1 Antibody (E-9) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

OR56B1 Antibody (E-9) Specifications

Alternate Product Name: OR56B1

Product Clone Name: E-9

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 187-206

Epitope Target: OR56B1

Epitope Species: human

Product Reactivity/Detection: OR56B1

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for OR56B1 Antibody (E-9): P: Blocking Peptide