
Oct-3/4 Antibody (A-9) is a mouse monoclonal IgG1 antibody that detects amino acids 16-45 near the N-terminus of Oct-3/4 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Oct-3/4 monoclonal antibody (A-9) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. POU5F1, also known as Oct-3/4, plays a critical role in maintaining pluripotency and self-renewal of embryonic stem cells, which is essential for early development and tissue regeneration. Oct-3/4 (A-9) antibody targets this transcription factor in the nucleus, where Oct-3/4 binds to specific DNA sequences to regulate gene expression involved in stem cell maintenance and differentiation. Oct-3/4′s ability to modulate gene expression is vital for proper development of various tissues and organs, and dysregulation can lead to developmental disorders and cancer. In humans, two isoforms of Oct-3/4 influence the undifferentiated state of embryonic stem cells, while pseudogenes associated with Oct-3/4 are transcribed in certain cancer cell lines, highlighting Oct-3/4′s importance in both normal physiology and disease states. Oct-3/4 (A-9) monoclonal antibody provides a versatile tool for detecting and studying Oct-3/4′s critical functions in stem cell biology, development, and disease research.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Oct3/4 Antibody (A-9) | sc-365509 | 200 µg/ml | $322.00 | |||
Oct3/4 Antibody (A-9): m-IgGλ BP-HRP Bundle | sc-522262 | 200 µg Ab, 40 µg BP | $361.00 | |||
Oct3/4 Antibody (A-9) X | sc-365509 X | 200 µg/0.1 ml | $322.00 | |||
Oct3/4 Antibody (A-9) AC | sc-365509 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Oct3/4 Antibody (A-9) HRP | sc-365509 HRP | 200 µg/ml | $322.00 | |||
Oct3/4 Antibody (A-9) FITC | sc-365509 FITC | 200 µg/ml | $336.00 | |||
Oct3/4 Antibody (A-9) PE | sc-365509 PE | 200 µg/ml | $349.00 | |||
Oct3/4 Antibody (A-9) Alexa Fluor® 488 | sc-365509 AF488 | 200 µg/ml | $364.00 | |||
Oct3/4 Antibody (A-9) Alexa Fluor® 546 | sc-365509 AF546 | 200 µg/ml | $364.00 | |||
Oct3/4 Antibody (A-9) Alexa Fluor® 594 | sc-365509 AF594 | 200 µg/ml | $364.00 | |||
Oct3/4 Antibody (A-9) Alexa Fluor® 647 | sc-365509 AF647 | 200 µg/ml | $364.00 | |||
Oct3/4 Antibody (A-9) Alexa Fluor® 680 | sc-365509 AF680 | 200 µg/ml | $364.00 | |||
Oct3/4 Antibody (A-9) Alexa Fluor® 790 | sc-365509 AF790 | 200 µg/ml | $364.00 | |||
Oct3/4 (A-9) Neutralizing Peptide | sc-365509 P | 100 µg/0.5 ml | $69.00 |