Molecular structure of O-Arachidonoyl Glycidol, CAS Number: 439146-24-4
O-Arachidonoyl Glycidol (CAS 439146-24-4)
Alternate Names:
5Z,8Z,11Z,14Z-eicosatetraenoic acid, oxiranylmethyl ester
Application:
O-Arachidonoyl Glycidol is a 2-AG analog which inhibits glycerol and arachidonoyl ethanolamide hydrolysis
CAS Number:
439146-24-4
Molecular Weight:
360.5
Molecular Formula:
C23H36O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
O-Arachidonoyl glycidol is a 2-Arachidonoyl glycerol (2-AG) analog that blocks 2-oleoyl glycerol hydrolysis in the cytosolic and membrane fractions of rat cerebella (IC50 = 4.5 and 19 muM, respectively). 2-AG is an endogenous ligand that binds to both central cannabinoid and peripheral cannabinoid receptors. O-Arachidonoyl glycidol also inhibits FAAH (fatty acid amide hydrolase)-catalyzed hydrolysis of arachidonoyl ethanolamide in the membrane fraction of rat cerebella (IC50 = 12 muM). It is involved in the regulation of a broad range of neurotransmitter signaling functions with implications in neurodegenerative diseases, pain, cancer, and obesity. O-Arachidonoyl Glycidol has inhibitory activity against Monoglyceride Lipase (monoacylglycerol lipase) and FAAH (fatty acid amide hydrolase).
O-Arachidonoyl Glycidol (CAS 439146-24-4) References
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Inhibitor of:
FAAH, and Monoglyceride Lipase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
O-Arachidonoyl Glycidol, 5 mg | sc-222087 | 5 mg | $86.00 | |||
O-Arachidonoyl Glycidol, 10 mg | sc-222087A | 10 mg | $165.00 |