Nrl Antibody (A-6): sc-398046
- Nrl Antibody (A-6) is a mouse monoclonal IgG3 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 42-69 within an internal region of Nrl of human origin
- recommended for detection of Nrl of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including bovine
- TransCruz reagent for ChIP application (sc-398046 X, 200 µg/0.1 ml)
- m-IgG3 BP-HRP is the preferred secondary detection reagent for Nrl Antibody (A-6) for WB applications. This reagent is now offered in a bundle with Nrl Antibody (A-6) (see ordering information below).
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SEE ALSO...
Nrl Antibody (A-6) is a mouse monoclonal IgG3 antibody that detects Nrl in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Nrl, or neural retina leucine zipper, is a crucial transcription factor belonging to the Maf family, characterized by a highly conserved basic leucine zipper (bZIP) domain that facilitates DNA binding. Nrl (A-6) antibody helps researchers study a protein that plays a vital role in retinal cell development and function, particularly in promoting rhodopsin expression, a key protein necessary for phototransduction in photoreceptor cells. Nrl achieves this by binding to the Nrl response element within the rhodopsin promoter, thereby regulating gene expression essential for vision. Additionally, anti-Nrl antibody (A-6) enables detection of Nrl expression throughout the developing central and peripheral nervous systems, highlighting its importance in neuronal differentiation, while expression becomes restricted to specific neuronal populations, including those in the neocortex, brainstem, and retina during adulthood. Nrl monoclonal antibody (A-6) serves as an invaluable tool for researchers studying retinal development and function, as well as the underlying mechanisms of visual disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nrl Antibody (A-6) | sc-398046 | 200 µg/ml | $322.00 | |||
Nrl Antibody (A-6): m-IgG3 BP-HRP Bundle | sc-550503 | 200 µg Ab; 40 µg BP | $361.00 | |||
Nrl (A-6) Neutralizing Peptide | sc-398046 P | 100 µg/0.5 ml | $69.00 | |||
Nrl Antibody (A-6) X | sc-398046 X | 200 µg/0.1 ml | $322.00 |