NR5A2 Antibody (E-9): sc-398349
- NR5A2 Antibody (E-9) is a mouse monoclonal mouse IgM κ κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 2-15 at the N-terminus of NR5A2 of mouse origin
- recommended for detection of all NR5A2 isoforms of mouse, rat and human origin by WB, IP, IF and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for NR5A2 Antibody (E-9). This work is in progress.
QUICK LINKS
SEE ALSO...
NR5A2 Antibody (E-9) is a mouse monoclonal IgM antibody that detects NR5A2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). NR5A2, also known as B1-binding factor (B1F or B1F2), CYP7A promoter-binding factor (CPF), fetoprotein-alpha 1 (AFP) transcription factor (FTF, FTZ-F1, or FTZ-F1β), and liver receptor homolog 1 (LRH-1), plays a crucial role as a pre-adipocyte-specific nuclear receptor that regulates aromatase expression in adipose tissue. NR5A2 is predominantly expressed in tissues of endodermal origin, with high transcript levels found in human ovary and testis. NR5A2 functions as a positive transcription factor for ATP-binding cassette transporters ABCG5 and ABCG8, which are essential for sterol and bile acid secretion regulation from liver and intestine. NR5A2 is involved in cell proliferation by inducing cyclin D1 and E1, an effect enhanced through β-catenin interaction, highlighting NR5A2′s importance in cellular growth and metabolic processes. Anti-NR5A2 antibody (E-9) serves as an invaluable tool for researchers studying this protein′s intricate roles in various biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NR5A2 Antibody (E-9) | sc-398349 | 200 µg/ml | $322.00 | |||
NR5A2 (E-9) Neutralizing Peptide | sc-398349 P | 100 µg/0.5 ml | $69.00 |