Notch 4 Antibody (C-3): sc-377399
- Notch 4 Antibody (C-3) is a mouse monoclonal IgG3 κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 3-31 near the N-terminus of Notch 4 of mouse origin
- recommended for detection of Notch 4 of mouse and rat origin by WB, IP, IF, IHC(P) and ELISA
- See Notch 4 (A-12): sc-393893 for Notch 4 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Notch 4 Antibody (C-3). This work is in progress.
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Notch 4 Antibody (C-3) is a mouse monoclonal IgG3 antibody that detects Notch 4 in mouse and rat samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Notch 4 is a crucial member of the Notch signaling pathway, which is integral to cell communication and plays a significant role in regulating cell fate decisions during development. Notch 4 protein is primarily located in the cell membrane, where anti-Notch 4 antibody (C-3) recognizes receptor interactions with ligands such as Jagged1, Jagged2, and Delta, facilitating essential processes like cell differentiation and tissue development. Proper functioning of Notch 4 is vital, as dysregulation of this pathway has been implicated in various cancers and developmental disorders. Notch 4′s structure, characterized by its extracellular domain, transmembrane region, and intracellular domain, is essential for ligand interaction and subsequent signal transduction, highlighting Notch 4′s importance in maintaining cellular homeostasis and influencing developmental pathways. With broad reactivity and versatile applications, Notch 4 (C-3) antibody serves as an invaluable tool for researchers investigating the complexities of cell signaling and development.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Notch 4 Antibody (C-3) | sc-377399 | 200 µg/ml | $322.00 | |||
Notch 4 (C-3) Neutralizing Peptide | sc-377399 P | 100 µg/0.5 ml | $69.00 |