NOP16 Antibody (JJ-39): sc-81866

NOP16 Antibody (JJ-39) is a mouse monoclonal IgG1 kappa light chain antibody that detects NOP16 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). NOP16 (JJ-39) antibody is available as the non-conjugated form. NOP16 plays a crucial role in ribosome biogenesis and is involved in the assembly of ribonucleoprotein complexes, which are essential for protein synthesis in cells. This function ensures proper translation of mRNA into proteins, a process vital for cellular function and growth. Disruptions in ribosome biogenesis can lead to various diseases, including cancer and genetic disorders, highlighting NOP16′s significance in maintaining cellular homeostasis. Additionally, chromosome 5, where NOP16 is located, is associated with several syndromes, including Cockayne syndrome and familial adenomatous polyposis, further emphasizing NOP16′s importance in human health and disease.

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NOP16 Antibody (JJ-39) References:

1. Duodenal adenomatosis in familial adenomatous polyposis coli. A review of the literature and results from the Heidelberg Polyposis Register.  |  Kadmon, M., et al. 2001. Int J Colorectal Dis. 16: 63-75. PMID: 11355321
2. The gene for Treacher Collins syndrome maps to the long arm of chromosome 5.  |  Dixon, MJ., et al. 1991. Am J Hum Genet. 49: 17-22. PMID: 1676560
3. Cockayne syndrome exhibits dysregulation of p21 and other gene products that may be independent of transcription-coupled repair.  |  Cleaver, JE., et al. 2007. Neuroscience. 145: 1300-8. PMID: 17055654
4. A new genomic mechanism leading to cri-du-chat syndrome.  |  South, ST., et al. 2006. Am J Med Genet A. 140: 2714-20. PMID: 17103439
5. Redefining monosomy 5 by molecular cytogenetics in 23 patients with MDS/AML.  |  Herry, A., et al. 2007. Eur J Haematol. 78: 457-67. PMID: 17391336
6. Somatic APC mosaicism: a frequent cause of familial adenomatous polyposis (FAP).  |  Aretz, S., et al. 2007. Hum Mutat. 28: 985-92. PMID: 17486639
7. Telomerase reverse transcriptase haploinsufficiency and telomere length in individuals with 5p- syndrome.  |  Du, HY., et al. 2007. Aging Cell. 6: 689-97. PMID: 17875000
8. Molecular mechanisms of skin aging: state of the art.  |  Makrantonaki, E. and Zouboulis, CC. 2007. Ann N Y Acad Sci. 1119: 40-50. PMID: 18056953
9. A physical map of 15 loci on human chromosome 5q23-q33 by two-color fluorescence in situ hybridization.  |  Saltman, DL., et al. 1993. Genomics. 16: 726-32. PMID: 8325647

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-NOP16 Antibody (JJ-39) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-NOP16 Antibody (JJ-39) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

NOP16 Antibody (JJ-39) Specifications

Alternate Product Name: NOP16

Product Clone Name: JJ-39

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 1-179

Epitope Target: NOP16

Epitope Species: human

Product Reactivity/Detection: NOP16

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 100 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for NOP16 Antibody (JJ-39): N/A