nm23-H7 Antibody (F-7): sc-166510
- nm23-H7 Antibody (F-7) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against amino acids 100-376 mapping at the C-terminus of nm23-H7 of human origin
- recommended for detection of nm23-H7 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for nm23-H7 Antibody (F-7) for WB applications. These reagents are now offered in bundles with nm23-H7 Antibody (F-7) (see ordering information below).
nm23-H7 Antibody (F-7) is a mouse monoclonal IgG2a antibody that detects nm23-H7 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). nm23-H7, also known as NME7 (non-metastatic cells 7), is a 376 amino acid protein that contains one DM10 domain and belongs to the nucleoside diphosphate kinase (NDK) family. nm23-H7 plays a crucial role in cellular metabolism by catalyzing the ATP-dependent synthesis of nucleoside triphosphates, which are vital for various metabolic pathways, including DNA and RNA synthesis, energy transfer, and signal transduction. The gene encoding nm23-H7 is located on human chromosome 1, a region spanning 260 million base pairs and containing over 3,000 genes, with significant associations to numerous diseases, including various cancers and genetic disorders. Proper functioning of nm23-H7 is essential for maintaining cellular homeostasis, and dysregulation has been implicated in tumor progression and metastasis, making nm23-H7 a critical target for cancer research and therapeutic interventions. anti-nm23-H7 antibody (F-7) serves as an invaluable tool for researchers exploring this protein′s intricate roles in health and disease.
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nm23-H7 Antibody (F-7) References:
- Expression of the nm23 homologues nm23-H4, nm23-H6, and nm23-H7 in human gastric and colon cancer. | Seifert, M., et al. 2005. J Pathol. 205: 623-32. PMID: 15726650
- Situs inversus in Dpcd/Poll-/-, Nme7-/-, and Pkd1l1-/- mice. | Vogel, P., et al. 2010. Vet Pathol. 47: 120-31. PMID: 20080492
- A shRNA functional screen reveals Nme6 and Nme7 are crucial for embryonic stem cell renewal. | Wang, CH., et al. 2012. Stem Cells. 30: 2199-211. PMID: 22899353
- NME7 is a functional component of the γ-tubulin ring complex. | Liu, P., et al. 2014. Mol Biol Cell. 25: 2017-25. PMID: 24807905
- A Homozygous Nme7 Mutation Is Associated with Situs Inversus Totalis. | Reish, O., et al. 2016. Hum Mutat. 37: 727-31. PMID: 27060491
- Expression profiling of Nme7 interactome in experimental models of metabolic syndrome. | Šedová, L., et al. 2018. Physiol Res. 67: S543-S550. PMID: 30484681
- Semi-Lethal Primary Ciliary Dyskinesia in Rats Lacking the Nme7 Gene. | Šedová, L., et al. 2021. Int J Mol Sci. 22: PMID: 33916973
- Heterozygous Nme7 Mutation Affects Glucose Tolerance in Male Rats. | Šedová, L., et al. 2021. Genes (Basel). 12: PMID: 34356103
- The Protein Kinase Activity of NME7 Activates Wnt/β-Catenin Signaling to Promote One-Carbon Metabolism in Hepatocellular Carcinoma. | Ren, X., et al. 2022. Cancer Res. 82: 60-74. PMID: 34764205
- NME7 maintains primary cilium assembly, ciliary microtubule stability, and Hedgehog signaling. | Ji, M., et al. 2025. Life Sci Alliance. 8: PMID: 39824631
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
nm23-H7 Antibody (F-7) | sc-166510 | 200 µg/ml | $322.00 | |||
nm23-H7 Antibody (F-7): m-IgG Fc BP-HRP Bundle | sc-537497 | 200 µg Ab; 10 µg BP | $361.00 | |||
nm23-H7 Antibody (F-7): m-IgGκ BP-HRP Bundle | sc-534779 | 200 µg Ab; 40 µg BP | $361.00 | |||
nm23-H7 Antibody (F-7): m-IgG2a BP-HRP Bundle | sc-548032 | 200 µg Ab; 10 µg BP | $361.00 |