NGFR p75 Antibody (2LA1): sc-71692

NGFR p75 Antibody (2LA1) is a mouse monoclonal IgG1 antibody that detects NGFR p75 in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). NGFR p75, also known as the p75 neurotrophin receptor, plays a crucial role in the nervous system by modulating the effects of neurotrophic factors, including nerve growth factor (NGF). NGFR p75 is primarily located on the surface of neurons and glial cells, where NGFR p75 acts as a co-receptor that enhances the signaling of neurotrophic factors, thereby influencing neuronal survival, differentiation, and apoptosis. The interaction between NGFR p75 and neurotrophic factors is essential for the proper development and maintenance of the nervous system, as NGFR p75 helps to fine-tune the signaling pathways that regulate neuronal health and function. Additionally, NGFR p75 can form complexes with other receptors, such as TrkA, to facilitate more effective signaling cascades, highlighting NGFR p75′s importance in neurobiology. Anti-NGFR p75 antibody (2LA1) is an invaluable tool for researchers studying neurotrophic signaling and its implications in neurodegenerative diseases and neuronal injury.

The preferred NGFR p75 antibody is NGFR p75 Antibody (ME20.4): sc-13577.