NGAL Antibody (HYB 211-01): sc-59622
- NGAL Antibody (HYB 211-01) is a mouse monoclonal IgG1, cited in 1 publications, provided at 100 µg/ml
- raised against full length native NGAL isolated from neutrophils of human origin
- recommended for detection of native and denatured forms of NGAL of human origin by WB, IF and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for NGAL Antibody (HYB 211-01). This work is in progress.
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NGAL Antibody (HYB 211-01) is a mouse monoclonal IgG1 antibody that detects NGAL in human samples through applications such as western blotting (WB), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). NGAL, or neutrophil gelatinase-associated lipocalin, plays a crucial role in the immune response, particularly in inflammatory processes. NGAL is primarily located in the extracellular space, where secretion occurs by activated leukocytes and epithelial cells during inflammation. This localization allows NGAL to interact with various immune cells and modulate their activity, thereby influencing the overall inflammatory response. NGAL has been shown to bind to bacterial products, suggesting a function as a scavenger that helps mitigate inflammation and protect tissues from damage during immune responses. NGAL′s ability to act as an inflammatory marker makes anti-NGAL antibody (HYB 211-01) a valuable tool for research into various diseases, including colorectal cancer and other inflammatory conditions. NGAL monoclonal antibody (HYB 211-01) provides specific reactivity and versatile applications for researchers studying the complex roles of NGAL in health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
NGAL Antibody (HYB 211-01) References:
- The multifaceted roles of neutrophil gelatinase associated lipocalin (NGAL) in inflammation and cancer. | Chakraborty, S., et al. 2012. Biochim Biophys Acta. 1826: 129-69. PMID: 22513004
- Neutrophil gelatinase-associated lipocalin in cancer. | Lippi, G., et al. 2014. Adv Clin Chem. 64: 179-219. PMID: 24938019
- The Central Role of Neutrophil Gelatinase-Associated Lipocalin in Cardiovascular Fibrosis. | Leopold, JA. 2015. Hypertension. 66: 20-2. PMID: 25987663
- Role of oncogene 24p3 neutrophil gelatinase-associated lipocalin (NGAL) in digestive system cancers. | Michalak, Ł., et al. 2016. Postepy Hig Med Dosw (Online). 70: 1026-1031. PMID: 27708207
- Neutrophil gelatinase-associated lipocalin: utility in urologic conditions. | Forster, CS. and Devarajan, P. 2017. Pediatr Nephrol. 32: 377-381. PMID: 27785626
- Neutrophil Gelatinase-Associated Lipocalin Levels During Pneumoperitoneum. | Kiseli, M., et al. 2017. JSLS. 21: PMID: 28144124
- Neutrophil gelatinase-associated lipocalin (NGAL) in kidney injury - A systematic review. | Marakala, V. 2022. Clin Chim Acta. 536: 135-141. PMID: 36150522
- Neutrophil gelatinase-associated lipocalin as an immunomodulator in endocrine hypertension. | Araos, P. and Amador, CA. 2022. Front Endocrinol (Lausanne). 13: 1006790. PMID: 36387895
- Urine neutrophil gelatinase-associated lipocalin as a biomarker of adult pyelonephritis. | Yamamoto, A., et al. 2023. J Infect Chemother. 29: 508-512. PMID: 36621764
- The Review of Current Knowledge on Neutrophil Gelatinase-Associated Lipocalin (NGAL). | Romejko, K., et al. 2023. Int J Mol Sci. 24: PMID: 37445650
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NGAL Antibody (HYB 211-01) | sc-59622 | 100 µg/ml | $322.00 |