NGAL Antibody (H-4): sc-518095
- NGAL Antibody (H-4) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 58-187 mapping within an internal region of NGAL of human origin
- NGAL Antibody (H-4) is recommended for detection of NGAL of human origin by WB, IP, IF and ELISA
- Anti-NGAL Antibody (H-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgGκ BP-HRP is the preferred secondary detection reagent for NGAL Antibody (H-4) for WB applications. This reagent is now offered in a bundle with NGAL Antibody (H-4) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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NGAL Antibody (H-4) is a mouse monoclonal IgG1 kappa light chain antibody that detects NGAL of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-NGAL antibody (H-4) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. NGAL, also known as lipocalin 2, plays a crucial role in the immune response and is primarily located in the extracellular space, where activated leukocytes and epithelial cells secrete NGAL . This localization enables NGAL to interact with various immune cells and modulate inflammatory responses, particularly during infection or tissue injury. NGAL binds to bacterial products, suggesting a scavenger function that helps mitigate inflammation and promote tissue repair. Additionally, NGAL shows upregulation in various pathological conditions, including inflammatory and neoplastic diseases, making NGAL a valuable biomarker for monitoring disease progression and response to therapy. With diverse applications and a critical role in immune modulation, NGAL (H-4) monoclonal antibody serves as an essential tool for researchers studying inflammation and related diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
NGAL Antibody (H-4) References:
- Roles of neutrophil gelatinase-associated lipocalin (NGAL) in human cancer. | Candido, S., et al. 2014. Oncotarget. 5: 1576-94. PMID: 24742531
- Urinary Neutrophil Gelatinase-Associated Lipocalin (NGAL) in Patients with Obstructive Sleep Apnea. | Maski, MR., et al. 2016. PLoS One. 11: e0154503. PMID: 27149121
- Predictive utilities of neutrophil gelatinase-associated lipocalin (NGAL) in severe sepsis. | Chang, W., et al. 2018. Clin Chim Acta. 481: 200-206. PMID: 29572184
- Expression of neutrophil gelatinase-associated lipocalin (NGAL) in the gut in Crohn's disease. | Thorsvik, S., et al. 2018. Cell Tissue Res. 374: 339-348. PMID: 29869714
- Neutrophil gelatinase-associated lipocalin (NGAL) and cardiovascular events in patients with stable coronary artery disease. | Sivalingam, Z., et al. 2018. Scand J Clin Lab Invest. 78: 470-476. PMID: 30261750
- Neutrophil Gelatinase Associated Lipocalin (NGAL) for Identification of Unstable Plaques in Patients with Asymptomatic Carotid Stenosis. | Eilenberg, W., et al. 2019. Eur J Vasc Endovasc Surg. 57: 768-777. PMID: 31164272
- Neutrophil gelatinase-associated lipocalin as a biomarker of nephropathy in sickle cell disease. | Marouf, R., et al. 2021. Ann Hematol. 100: 1401-1409. PMID: 33796899
- Predictive Value of Elevated Neutrophil Gelatinase-Associated Lipocalin (NGAL) Levels for Assessment of Cardio-Renal Interactions among ST-Segment Elevation Myocardial Infarction Patients. | Zahler, D., et al. 2022. J Clin Med. 11: PMID: 35456255
- Neutrophil Gelatinase-Associated Lipocalin (NGAL) and cystatin C are early biomarkers of acute kidney injury associated with cardiac surgery. | Larstorp, ACK., et al. 2022. Scand J Clin Lab Invest. 82: 410-418. PMID: 36036280
- Neutrophil gelatinase-associated lipocalin (NGAL) and tumor necrosis factor-α (TNF-α) levels in patients with schizophrenia. | Gül Çakıl, A., et al. 2023. Psychopharmacology (Berl). 240: 1091-1101. PMID: 36877232
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NGAL Antibody (H-4) | sc-518095 | 200 µg/ml | $316.00 | |||
NGAL Antibody (H-4): m-IgGκ BP-HRP Bundle | sc-525364 | 200 µg Ab, 40 µg BP | $354.00 | |||
NGAL Antibody (H-4) AC | sc-518095 AC | 500 µg/ml, 25% agarose | $416.00 | |||
NGAL Antibody (H-4) HRP | sc-518095 HRP | 200 µg/ml | $316.00 | |||
NGAL Antibody (H-4) FITC | sc-518095 FITC | 200 µg/ml | $330.00 | |||
NGAL Antibody (H-4) PE | sc-518095 PE | 200 µg/ml | $343.00 | |||
NGAL Antibody (H-4) Alexa Fluor® 488 | sc-518095 AF488 | 200 µg/ml | $357.00 | |||
NGAL Antibody (H-4) Alexa Fluor® 546 | sc-518095 AF546 | 200 µg/ml | $357.00 | |||
NGAL Antibody (H-4) Alexa Fluor® 594 | sc-518095 AF594 | 200 µg/ml | $357.00 | |||
NGAL Antibody (H-4) Alexa Fluor® 647 | sc-518095 AF647 | 200 µg/ml | $357.00 | |||
NGAL Antibody (H-4) Alexa Fluor® 680 | sc-518095 AF680 | 200 µg/ml | $357.00 | |||
NGAL Antibody (H-4) Alexa Fluor® 790 | sc-518095 AF790 | 200 µg/ml | $357.00 |