NG2 Antibody (4D1): sc-47718
- NG2 Antibody (4D1) is a mouse monoclonal IgM κ, cited in 2 publications, provided at 200 µg/ml
- raised against NG2 derived from aorta tissue homogenate of bovine origin
- Anti-NG2 Antibody (4D1) is recommended for detection of NG2 of mouse, rat and human origin by WB, IP, IF and IHC(P); also reactive with additional species, including bovine
- Anti-NG2 Antibody (4D1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for NG2 Antibody (4D1). This work is in progress.
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SEE ALSO...
NG2 Antibody (4D1) is a mouse monoclonal IgM antibody that detects NG2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Anti-NG2 antibody (4D1) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. NG2, also known as neuron-glial antigen 2, plays a crucial role in the development and maintenance of the nervous system, particularly in the regulation of glial cell proliferation and differentiation. NG2 is primarily located in the extracellular matrix and is associated with the surface of oligodendrocyte precursor cells, where NG2 contributes to cell signaling and communication within the central nervous system. NG2 expression is vital for the proper functioning of these precursor cells, as NG2 influences their ability to migrate, proliferate, and differentiate into mature oligodendrocytes, which are essential for myelination and overall neuronal health. NG2 is involved in various pathological conditions, including brain tumors and multiple sclerosis, making NG2 a significant target for research in neurobiology and regenerative medicine. The 4D1 clone was developed through immunization of Balb/c female mice with a versican-containing preparation from bovine aorta, predigested with endo-β-galactosidase and keratanase II, and specifically reacts with native chondroitin-4-sulfate, a critical component of glycosaminoglycans that contribute to the structural integrity and function of the extracellular matrix.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NG2 Antibody (4D1) | sc-47718 | 200 µg/ml | $322.00 | |||
NG2 Antibody (4D1) AC | sc-47718 AC | 500 µg/ml, 25% agarose | $424.00 | |||
NG2 Antibody (4D1) HRP | sc-47718 HRP | 200 µg/ml | $322.00 | |||
NG2 Antibody (4D1) FITC | sc-47718 FITC | 200 µg/ml | $336.00 | |||
NG2 Antibody (4D1) PE | sc-47718 PE | 200 µg/ml | $349.00 | |||
NG2 Antibody (4D1) Alexa Fluor® 488 | sc-47718 AF488 | 200 µg/ml | $364.00 | |||
NG2 Antibody (4D1) Alexa Fluor® 546 | sc-47718 AF546 | 200 µg/ml | $364.00 | |||
NG2 Antibody (4D1) Alexa Fluor® 594 | sc-47718 AF594 | 200 µg/ml | $364.00 | |||
NG2 Antibody (4D1) Alexa Fluor® 647 | sc-47718 AF647 | 200 µg/ml | $364.00 | |||
NG2 Antibody (4D1) Alexa Fluor® 680 | sc-47718 AF680 | 200 µg/ml | $364.00 | |||
NG2 Antibody (4D1) Alexa Fluor® 790 | sc-47718 AF790 | 200 µg/ml | $364.00 |