Date published: 2026-5-3

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NFPS (CAS 405225-21-0)

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Alternate Names:
2-[[3-(4-fluorophenyl)-3-(4-phenylphenoxy)propyl]-methylamino]acetic acid
Application:
NFPS is a non-transportable inhibitor of GlyT1
CAS Number:
405225-21-0
Purity:
≥98%
Molecular Weight:
393.45
Molecular Formula:
C24H24FNO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.

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Non-transportable inhibitor of GlyT1. Displays no activity on GlyT2 or the transport of GABA, Glu, or Pro. Enhances amplitude of NMDA component of glutamatergic EPSCs.


NFPS (CAS 405225-21-0) References

Bergeron et al (1998) Modulation of N-methyl-D-aspartate receptor function by glycine transport. Proc.Natl.Acad.Sci.USA 95 15730. Harsing Jr. et al (2003) The glycine transporter-1 inhibitors NFPS and Org 24461: a pharmacological study. Pharmacol.Biochem.Behav. 74 811. Mallorga et al (2003) Pharmacology and expression analysis of glycine transporter GlyT1 with [3H]-(N-[3-(4'-fluorophenyl)-3-(4'phenylphenoxy)propyl])sarcosine. Neuropharmacology 45 585.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

NFPS, 10 mg

sc-204126
10 mg
$195.00
US: Only available in the US

NFPS, 50 mg

sc-204126A
50 mg
$849.00
US: Only available in the US